@article{74f1a20adc7b4dd8afe7596233117a8f,
title = "A closely-related clade of globally distributed bloom-forming cyanobacteria within the Nostocales",
abstract = "In order to better understand the relationships among current Nostocales cyanobacterial blooms, eight genomes were sequenced from cultured isolates or from environmental metagenomes of recent planktonic Nostocales blooms. Phylogenomic analysis of publicly available sequences placed the new genomes among a group of 15 genomes from four continents in a distinct ADA clade (Anabaena/Dolichospermum/Aphanizomenon) within the Nostocales. This clade contains four species-level groups, two of which include members with both Anabaena-like and Aphanizomenon flos-aquae-like morphology. The genomes contain many repetitive genetic elements and a sizable pangenome, in which ABC-type transporters are highly represented. Alongside common core genes for photosynthesis, the differentiation of N2-fixing heterocysts, and the uptake and incorporation of the major nutrients P, N and S, we identified several gene pathways in the pangenome that may contribute to niche partitioning. Genes for problematic secondary metabolites—cyanotoxins and taste-and-odor compounds—were sporadically present, as were other polyketide synthase (PKS) and nonribosomal peptide synthetase (NRPS) gene clusters. By contrast, genes predicted to encode the ribosomally generated bacteriocin peptides were found in all genomes.",
keywords = "Filamentous cyanobacteria, Genomics, Metagenomics",
author = "Driscoll, {Connor B.} and Meyer, {Kevin A.} and Sigitas {\v S}ul{\v c}ius and Brown, {Nathan M.} and Dick, {Gregory J.} and Huansheng Cao and Giedrius Gasiūnas and Albertas Timinskas and Yanbin Yin and Landry, {Zachary C.} and Otten, {Timothy G.} and Davis, {Timothy W.} and Watson, {Susan B.} and Dreher, {Theo W.}",
note = "Funding Information: The research at Oregon State University was supported by U.S. Geological Survey grant 2012OR127G , the Oregon State University Agricultural Experiment Station , the Mabel E. Pernot Trust and the NL Tartar Research Fellowship . We thank Alexandra Weisberg for assistance with Mauve alignments. Research at the University of Michigan was supported by a grant from the Erb Family Foundation made through the University of Michigan Water Center (Grant N017871 ) and from the National Science Foundation (NSF OCE 1736629 ). The research at Nature Research Centre and Vilnius University was funded by a grant (No. S-LJB-17-1 ) from the Research Council of Lithuania to S{\v S} and GG. [CG] Funding Information: The research at Oregon State University was supported by U.S. Geological Survey grant 2012OR127G, the Oregon State University Agricultural Experiment Station, the Mabel E. Pernot Trust and the NL Tartar Research Fellowship. We thank Alexandra Weisberg for assistance with Mauve alignments. Research at the University of Michigan was supported by a grant from the Erb Family Foundation made through the University of Michigan Water Center (Grant N017871) and from theNational Science Foundation (NSF OCE 1736629). The research at Nature Research Centre and Vilnius University was funded by a grant (No. S-LJB-17-1) from the Research Council of Lithuania to S{\v S} and GG. [CG] Publisher Copyright: {\textcopyright} 2018",
year = "2018",
month = jul,
doi = "10.1016/j.hal.2018.05.009",
language = "English (US)",
volume = "77",
pages = "93--107",
journal = "Harmful Algae",
issn = "1568-9883",
publisher = "Elsevier",
}