12/15-Lipoxygenase is equired for the early onset of high fat diet-induced adipose tissue inflammation and insulin resistance in mice

Agriculture & Biology

• arachidonate 15-lipoxygenase 95%
• insulin resistance 73%
• high fat diet 64%
• adipose tissue 59%
• inflammation 54%
• mice 34%
• insulin 17%
• macrophages 11%
• chemokine CCL2 10%
• osteopontin 9%
• interleukin-12 8%
• chemokines 8%
• glucose 7%
• interleukin-10 7%
• interleukin-1 7%
• liver 7%
• atherosclerosis 7%
• interleukin-6 7%
• muscle tissues 6%
• cytokines 6%
• early development 6%
• skeletal muscle 6%
• species recruitment 5%
• phosphorylation 5%
• lipids 3%
• diet 3%
• tissues 2%
• genes 2%
• proteins 2%
• cells 2%
• methodology 1%

Medicine & Life Sciences

• 12-15-lipoxygenase 100%
• High Fat Diet 60%
• Adipose Tissue 49%
• Insulin Resistance 49%
• Inflammation 35%
• Knockout Mice 31%
• Insulin 17%
• Chemokines 16%
• Macrophages 11%
• Glucose 10%
• Glucose Clamp Technique 10%
• Osteopontin 10%
• Liver 8%
• Interleukin-12 8%
• Interleukin-1 8%
• Interleukin-10 7%
• Atherosclerosis 6%
• Skeletal Muscle 6%
• Interleukin-6 6%
• Fats 6%
• Phosphorylation 5%
• Diet 5%
• Cytokines 5%
• Muscles 5%
• Genes 3%
• Proteins 3%

Chemical Compounds

• Insulin Derivative 61%
• Fat 58%
• Resistance 37%
• Marker 13%
• Glucose 11%
• Protein 3%