Antigen Identification for Antibodies against Bacillus anthracis Utilizing Nucleic Acid Programmable Protein Arrays (NAPPA) Technology

Project: Research project

Description

This work will employ nucleic acid programmable protein arrays (NAPPA) as a rapid and flexible capability for identifying the antigen targets recognized by antibodies raised against Bacillus anthracis from the Critical Reagents Program (CRP). In six months we will have constructed NAPPA arrays comprising all B.a. outer membrane proteins. By the end of the first year we will have antigen target identified for all available B.a. antibodies.
StatusFinished
Effective start/end date6/16/143/29/15

Funding

  • DOD-ARMY: Edgewood Chemical Biological Center (ECBC): $110,892.00

Fingerprint

Bacillus anthracis
Protein Array Analysis
Nucleic Acids
Technology
Antigens
Antibodies
Membrane Proteins