Research Output per year
Personal profile
Education/Academic qualification
PHD, University of Rochester
… → 1970
BA, University of Illinois-Chicago
… → 1966
Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.
- 2 Similar Profiles
Bleomycin
Chemical Compounds
DNA
Chemical Compounds
Transfer RNA
Chemical Compounds
DNA Cleavage
Medicine & Life Sciences
Type I DNA Topoisomerase
Medicine & Life Sciences
DNA Polymerase beta
Chemical Compounds
Camptothecin
Medicine & Life Sciences
Derivatives
Chemical Compounds
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Research Output 1966 2018
Chemical synthesis of lipophilic methylene blue analogues which increase mitochondrial biogenesis and frataxin levels
Bandyopadhyay, I., Chowdhury, S. R., Visavadiya, N. P., Hecht, S. & Khdour, O., Oct 1 2018, In : Data in Brief. 20, p. 1105-1114 10 p.Research output: Contribution to journal › Article
Neurodegenerative diseases
Methylene Blue
frataxin
3
Citations
Lipophilic methylene blue analogues enhance mitochondrial function and increase frataxin levels in a cellular model of Friedreich's ataxia
Khdour, O., Bandyopadhyay, I., Chowdhury, S. R., Visavadiya, N. P. & Hecht, S., Jan 1 2018, (Accepted/In press) In : Bioorganic and Medicinal Chemistry.Research output: Contribution to journal › Article
Friedreich Ataxia
Methylene Blue
Lymphocytes
Neurodegenerative Diseases
Aconitate Hydratase
2
Citations
Oligomeric amyloid β preferentially targets neuronal and not glial mitochondrial-encoded mRNAs
Mastroeni, D., Nolz, J., Khdour, O., Sekar, S., Delvaux, E., Cuyugan, L., Liang, W. S., Hecht, S. & Coleman, P., Jan 1 2018, (Accepted/In press) In : Alzheimer's and Dementia.Research output: Contribution to journal › Article
coenzyme Q10
Amyloid
Neuroglia
Neurons
Alzheimer Disease
Phenothiazine antioxidants increase mitochondrial biogenesis and frataxin levels in Friedreich's ataxia cells
Khdour, O., Bandyopadhyay, I., Visavadiya, N. P., Roy Chowdhury, S. & Hecht, S., Jan 1 2018, In : MedChemComm. 9, 9, p. 1491-1501 11 p.Research output: Contribution to journal › Article
Friedreich Ataxia
Organelle Biogenesis
Antioxidants
Methylene Blue
Substitution reactions
1
Citations
Rapid detection of a dengue virus RNA sequence with single molecule sensitivity using tandem toehold-mediated displacement reactions
Gao, M., Daniel, D., Zou, H., Jiang, S., Lin, S., Huang, C., Hecht, S. & Chen, S., Jan 1 2018, In : Chemical Communications. 54, 8, p. 968-971 4 p.Research output: Contribution to journal › Article
RNA
Viruses
DNA
Molecules
Amplification
Projects 2008 2021
Optimization of Methylene Blue Derivatives as Mitochondrial Therapeutic Agents for the Treatment of Freidreich's Ataxia
Friedreich's Ataxia Research Alliance
1/1/18 → 12/31/19
Project: Research project
Optimization of Methylene Blue Derivatives as Mitochondrial Therapeutic Agents Fo
Friedreich's Ataxia Research Alliance
12/15/17 → 12/14/18
Project: Research project
Selection of Modified Ribosomes Using Novel Puromycins
Hecht, S., Chen, S. & Dedkova, L.
HHS-NIH: National Inst of General Medical Sciences (NIGMS)
12/1/17 → 11/30/21
Project: Research project
Ribosomally Synthesized Proteins Incorporating Modified Dipeptides
HHS-NIH: National Inst of General Medical Sciences (NIGMS)
7/15/17 → 5/31/21
Project: Research project
A Low-Cost Tool to Rapidly Detect Dengue Virus in the Field
DOD-ARMY: Army Med Research Acquisition Activity (USAMRAA)
6/1/16 → 2/28/18
Project: Research project