• 18179 Citations
  • 62 h-Index
1966 …2021
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Personal profile

Education/Academic qualification

PHD, University of Rochester

… → 1970

BA, University of Illinois-Chicago

… → 1966

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  • 2 Similar Profiles
Bleomycin Chemical Compounds
DNA Chemical Compounds
Transfer RNA Chemical Compounds
DNA Cleavage Medicine & Life Sciences
Type I DNA Topoisomerase Medicine & Life Sciences
DNA Polymerase beta Chemical Compounds
Camptothecin Medicine & Life Sciences
Derivatives Chemical Compounds

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Research Output 1966 2018

Chemical synthesis of lipophilic methylene blue analogues which increase mitochondrial biogenesis and frataxin levels

Bandyopadhyay, I., Chowdhury, S. R., Visavadiya, N. P., Hecht, S. & Khdour, O., Oct 1 2018, In : Data in Brief. 20, p. 1105-1114 10 p.

Research output: Contribution to journalArticle

Neurodegenerative diseases
Methylene Blue
frataxin
3 Citations

Lipophilic methylene blue analogues enhance mitochondrial function and increase frataxin levels in a cellular model of Friedreich's ataxia

Khdour, O., Bandyopadhyay, I., Chowdhury, S. R., Visavadiya, N. P. & Hecht, S., Jan 1 2018, (Accepted/In press) In : Bioorganic and Medicinal Chemistry.

Research output: Contribution to journalArticle

Friedreich Ataxia
Methylene Blue
Lymphocytes
Neurodegenerative Diseases
Aconitate Hydratase
2 Citations

Oligomeric amyloid β preferentially targets neuronal and not glial mitochondrial-encoded mRNAs

Mastroeni, D., Nolz, J., Khdour, O., Sekar, S., Delvaux, E., Cuyugan, L., Liang, W. S., Hecht, S. & Coleman, P., Jan 1 2018, (Accepted/In press) In : Alzheimer's and Dementia.

Research output: Contribution to journalArticle

coenzyme Q10
Amyloid
Neuroglia
Neurons
Alzheimer Disease

Phenothiazine antioxidants increase mitochondrial biogenesis and frataxin levels in Friedreich's ataxia cells

Khdour, O., Bandyopadhyay, I., Visavadiya, N. P., Roy Chowdhury, S. & Hecht, S., Jan 1 2018, In : MedChemComm. 9, 9, p. 1491-1501 11 p.

Research output: Contribution to journalArticle

Friedreich Ataxia
Organelle Biogenesis
Antioxidants
Methylene Blue
Substitution reactions
1 Citations

Rapid detection of a dengue virus RNA sequence with single molecule sensitivity using tandem toehold-mediated displacement reactions

Gao, M., Daniel, D., Zou, H., Jiang, S., Lin, S., Huang, C., Hecht, S. & Chen, S., Jan 1 2018, In : Chemical Communications. 54, 8, p. 968-971 4 p.

Research output: Contribution to journalArticle

RNA
Viruses
DNA
Molecules
Amplification

Projects 2008 2021