Sidney Hecht

Professor

Professor, Biodesign: Bioenergetics, Center for (BE)
Professor, CLAS-NS: Molecular Sciences, School of (SMS)
Professor, IAFSE-SEMTE: Chemical Engineering

Source: Scopus
Calculated based on no. of publications stored in Pure and citations from Scopus

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Personal profile

Education/Academic qualification

PHD, University of Rochester

… → 1970

BA, University of Illinois-Chicago

… → 1966

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19542 Citations
63 h-Index
425 Article
11 Patent
10 Letter
9 Comment/debate
13 More

Alteration of Transcriptional Regulator Rob In Vivo: Enhancement of Promoter DNA Binding and Antibiotic Resistance in the Presence of Nucleobase Amino Acids
Zhang, C., Chen, S., Bai, X., Dedkova, L. M. & Hecht, S. M., Mar 31 2020, In : Biochemistry. 59, 12, p. 1217-1220 4 p.
Research output: Contribution to journal › Article › peer-review
2 Scopus citations
An assay for DNA polymerase β lyase inhibitors that engage the catalytic nucleophile for binding
Daskalova, S. M., Eisenhauer, B. M., Gao, M., Feng, X., Ji, X., Cheng, Q., Fahmi, N. E., Khdour, O. M., Chen, S. & Hecht, S. M., Sep 1 2020, In : Bioorganic and Medicinal Chemistry. 28, 17, 115642.
Research output: Contribution to journal › Article › peer-review
Effects of Nucleobase Amino Acids on the Binding of Rob to Its Promoter DNA: Differential Alteration of DNA Affinity and Phenotype
Zhang, C., Chen, S., Dedkova, L. M. & Hecht, S. M., Jun 9 2020, In : Biochemistry. 59, 22, p. 2111-2119 9 p.
Research output: Contribution to journal › Article › peer-review
Novel idebenone analogs block Shc's access to insulin receptor to improve insulin sensitivity
Hui, C. K., Tomilov, A., Garcia, C., Jiang, X. S., Fash, D. M., Khdour, O. M., Rosso, C., Filippini, G., Prato, M., Graham, J., Hecht, S., Havel, P. & Cortopassi, G., Dec 2020, In : Biomedicine and Pharmacotherapy. 132, 110823.
Research output: Contribution to journal › Article › peer-review

Open Access
Protein synthesis with conformationally constrained cyclic dipeptides
Zhang, C., Bai, X., Dedkova, L. M. & Hecht, S. M., Nov 15 2020, In : Bioorganic and Medicinal Chemistry. 28, 22, 115780.
Research output: Contribution to journal › Article › peer-review

2 Active
21 Finished

Selection of Modified Ribosomes Using Novel Puromycins
Hecht, S., Chen, S. & Dedkova, L.
HHS-NIH: National Institute of General Medical Sciences (NIGMS)
12/1/17 → 11/30/21
Project: Research project
Ribosomally Synthesized Proteins Incorporating Modified Dipeptides
Hecht, S. & Dedkova, L.
HHS-NIH: National Institute of General Medical Sciences (NIGMS)
7/15/17 → 5/31/21
Project: Research project
Optimization of Methylene Blue Derivatives as Mitochondrial Therapeutic Agents for the Treatment of Freidreich's Ataxia
Khdour, O. & Hecht, S.
Friedreich's Ataxia Research Alliance
1/1/18 → 12/31/19
Project: Research project
Optimization of Methylene Blue Derivatives as Mitochondrial Therapeutic Agents Fo
Khdour, O. & Hecht, S.
Friedreich's Ataxia Research Alliance
12/15/17 → 12/14/18
Project: Research project
A Low-Cost Tool to Rapidly Detect Dengue Virus in the Field
Chen, S. & Hecht, S.
DOD-ARMY: Army Medical Research Acquisition Activity (USAMRAA)
6/1/16 → 2/28/18
Project: Research project