Sidney Hecht

Personal profile

Education/Academic qualification

PHD, University of Rochester

… → 1970

BA, University of Illinois-Chicago

… → 1966

Fingerprint Dive into the research topics where Sidney Hecht is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

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Bleomycin Chemical Compounds

DNA Chemical Compounds

Transfer RNA Medicine & Life Sciences

DNA Cleavage Medicine & Life Sciences

Type I DNA Topoisomerase Medicine & Life Sciences

Camptothecin Medicine & Life Sciences

Derivatives Chemical Compounds

Bioassay Chemical Compounds

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Research Output 1966 2019

18672 Citations
62 h-Index
446 Article
11 Patent
2 Chapter
2 Conference contribution
1 More
- 1 Comment/debate

Expanding the Scope of Protein Synthesis Using Modified Ribosomes

Dedkova, L. & Hecht, S., Apr 24 2019, In : Journal of the American Chemical Society. 141, 16, p. 6430-6447 18 p.

Research output: Contribution to journal › Article

Ribosomes

Peptides

Proteins

RNA

Amino acids

2 Citations (Scopus)

In Cellulo Synthesis of Proteins Containing a Fluorescent Oxazole Amino Acid

Chen, S., Ji, X., Gao, M., Dedkova, L. & Hecht, S., Apr 10 2019, In : Journal of the American Chemical Society. 141, 14, p. 5597-5601 5 p.

Research output: Contribution to journal › Article

Oxazoles

Amino acids

Proteins

Amino Acids

Escherichia coli

Chemical synthesis of lipophilic methylene blue analogues which increase mitochondrial biogenesis and frataxin levels

Bandyopadhyay, I., Chowdhury, S. R., Visavadiya, N. P., Hecht, S. & Khdour, O., Oct 1 2018, In : Data in Brief. 20, p. 1105-1114 10 p.

Research output: Contribution to journal › Article

Neurodegenerative diseases

Methylene Blue

frataxin

3 Citations (Scopus)

Lipophilic methylene blue analogues enhance mitochondrial function and increase frataxin levels in a cellular model of Friedreich's ataxia

Khdour, O., Bandyopadhyay, I., Chowdhury, S. R., Visavadiya, N. P. & Hecht, S., Jan 1 2018, (Accepted/In press) In : Bioorganic and Medicinal Chemistry.

Research output: Contribution to journal › Article

Friedreich Ataxia

Methylene Blue

Lymphocytes

Neurodegenerative Diseases

Aconitate Hydratase

5 Citations (Scopus)

Oligomeric amyloid β preferentially targets neuronal and not glial mitochondrial-encoded mRNAs

Mastroeni, D., Nolz, J., Khdour, O., Sekar, S., Delvaux, E., Cuyugan, L., Liang, W. S., Hecht, S. & Coleman, P., Jan 1 2018, (Accepted/In press) In : Alzheimer's and Dementia.

Research output: Contribution to journal › Article

coenzyme Q10

Amyloid

Neuroglia

Neurons

Alzheimer Disease