Sidney Hecht

Professor

Professor, Biodesign: Bioenergetics, Center for (BE)
Professor, CLAS-NS: Molecular Sciences, School of (SMS)
Professor, IAFSE-SEMTE: Chemical Engineering

Source: Scopus
Calculated based on no. of publications stored in Pure and citations from Scopus

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Personal profile

Education/Academic qualification

PHD, University of Rochester

… → 1970

BA, University of Illinois-Chicago

… → 1966

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19908 Citations
64 h-Index
425 Article
11 Patent
10 Letter
9 Comment/debate
More

Alteration of Transcriptional Regulator Rob In Vivo: Enhancement of Promoter DNA Binding and Antibiotic Resistance in the Presence of Nucleobase Amino Acids
Zhang, C., Chen, S., Bai, X., Dedkova, L. M. & Hecht, S. M., Mar 31 2020, In: Biochemistry. 59, 12, p. 1217-1220 4 p.
Research output: Contribution to journal › Article › peer-review
4 Scopus citations
An assay for DNA polymerase β lyase inhibitors that engage the catalytic nucleophile for binding
Daskalova, S. M., Eisenhauer, B. M., Gao, M., Feng, X., Ji, X., Cheng, Q., Fahmi, N. E., Khdour, O. M., Chen, S. & Hecht, S. M., Sep 1 2020, In: Bioorganic and Medicinal Chemistry. 28, 17, 115642.
Research output: Contribution to journal › Article › peer-review
Antiferroptotic Activity of Phenothiazine Analogues: A Novel Therapeutic Strategy for Oxidative Stress Related Disease
Liu, J., Bandyopadhyay, I., Zheng, L., Khdour, O. M. & Hecht, S. M., Nov 12 2020, In: ACS Medicinal Chemistry Letters. 11, 11, p. 2165-2173 9 p.
Research output: Contribution to journal › Article › peer-review
Effects of Nucleobase Amino Acids on the Binding of Rob to Its Promoter DNA: Differential Alteration of DNA Affinity and Phenotype
Zhang, C., Chen, S., Dedkova, L. M. & Hecht, S. M., Jun 9 2020, In: Biochemistry. 59, 22, p. 2111-2119 9 p.
Research output: Contribution to journal › Article › peer-review
1 Scopus citations
Novel idebenone analogs block Shc's access to insulin receptor to improve insulin sensitivity
Hui, C. K., Tomilov, A., Garcia, C., Jiang, X. S., Fash, D. M., Khdour, O. M., Rosso, C., Filippini, G., Prato, M., Graham, J., Hecht, S., Havel, P. & Cortopassi, G., Dec 2020, In: Biomedicine and Pharmacotherapy. 132, 110823.
Research output: Contribution to journal › Article › peer-review

Open Access

2 Active
22 Finished

Develop System for Synthesis of Receptor Binding Cyclic Polypeptides
Dedkova, L., Hecht, S., Khdour, O. & Chen, S.
INDUSTRY: Domestic Company
11/24/20 → 12/31/21
Project: Research project
Selection of Modified Ribosomes Using Novel Puromycins
Hecht, S., Chen, S. & Dedkova, L.
HHS-NIH: National Institute of General Medical Sciences (NIGMS)
12/1/17 → 11/30/21
Project: Research project
Optimization of Methylene Blue Derivatives as Mitochondrial Therapeutic Agents for the Treatment of Freidreich's Ataxia
Khdour, O. & Hecht, S.
Friedreich's Ataxia Research Alliance
1/1/18 → 12/31/19
Project: Research project
Optimization of Methylene Blue Derivatives as Mitochondrial Therapeutic Agents Fo
Khdour, O. & Hecht, S.
Friedreich's Ataxia Research Alliance
12/15/17 → 12/14/18
Project: Research project
Ribosomally Synthesized Proteins Incorporating Modified Dipeptides
Hecht, S. & Dedkova, L.
HHS-NIH: National Institute of General Medical Sciences (NIGMS)
7/15/17 → 5/31/21
Project: Research project