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Research Output 1995 2019

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2019

Microfluidic sample delivery for serial crystallography using XFELs

Echelmeier, A., Sonker, M. & Ros, A., Jan 1 2019, In : Analytical and bioanalytical chemistry.

Research output: Contribution to journalArticle

X ray lasers
Crystallography
Microfluidics
Free electron lasers
X Ray Crystallography
3 Citations (Scopus)

Snapshot of an oxygen intermediate in the catalytic reaction of cytochrome c oxidase

Ishigami, I., Lewis-Ballester, A., Echelmeier, A., Brehm, G., Zatsepin, N., Grant, T. D., Coe, J. D., Lisova, S., Nelson, G., Zhang, S., Dobson, Z. F., Boutet, S., Sierra, R. G., Batyuk, A., Fromme, P., Fromme, R., Spence, J., Ros, A., Yeh, S. R. & Rousseau, D. L., Feb 26 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 9, p. 3572-3577 6 p.

Research output: Contribution to journalArticle

Electron Transport Complex IV
Oxygen
Protons
Protein Conformation
Crystallography
2018
5 Citations (Scopus)

Deterministic Ratchet for Sub-micrometer (Bio)particle Separation

Kim, D., Luo, J., Arriaga, E. A. & Ros, A., Apr 3 2018, In : Analytical Chemistry. 90, 7, p. 4370-4379 10 p.

Research output: Contribution to journalArticle

Numerical models
Mitochondria
Microfluidics
Liposomes
Liver
2017
15 Citations (Scopus)

Continuous Separation of DNA Molecules by Size Using Insulator-Based Dielectrophoresis

Jones, P. V., Salmon, G. L. & Ros, A., Feb 7 2017, In : Analytical Chemistry. 89, 3, p. 1531-1539 9 p.

Research output: Contribution to journalArticle

Electrophoresis
Sorting
Molecules
DNA
Nucleic Acids
5 Citations (Scopus)

Single-Walled Carbon Nanotubes Probed with Insulator-Based Dielectrophoresis

Rabbani, M. T., Schmidt, C. F. & Ros, A., Dec 19 2017, In : Analytical Chemistry. 89, 24, p. 13235-13244 10 p.

Research output: Contribution to journalArticle

Single-walled carbon nanotubes (SWCN)
Electrophoresis
Suspensions
Electric properties
Optical properties
2016
8 Citations (Scopus)

Deterministic Absolute Negative Mobility for Micro- and Submicrometer Particles Induced in a Microfluidic Device

Luo, J., Muratore, K. A., Arriaga, E. A. & Ros, A., Jun 7 2016, In : Analytical Chemistry. 88, 11, p. 5920-5927 8 p.

Research output: Contribution to journalArticle

Microfluidics
Mitochondria
Liver
Nanocrystals
Nanoparticles
10 Citations (Scopus)

Protein Crystallization in an Actuated Microfluidic Nanowell Device

Abdallah, B. G., Roy-Chowdhury, S., Fromme, R., Fromme, P. & Ros, A., Apr 6 2016, In : Crystal Growth and Design. 16, 4, p. 2074-2082 9 p.

Research output: Contribution to journalArticle

microfluidic devices
Crystallization
Microfluidics
crystallization
proteins
17 Citations (Scopus)
Microfluidics
Mass spectrometry
Labeling
Proteins
Apoptosis
2015
13 Citations (Scopus)

High throughput protein nanocrystal fractionation in a microfluidic sorter

Abdallah, B. G., Roy-Chowdhury, S., Coe, J., Fromme, P. & Ros, A., Apr 21 2015, In : Analytical Chemistry. 87, 8, p. 4159-4167 9 p.

Research output: Contribution to journalArticle

Fractionation
Sorting
Microfluidics
Nanocrystals
Throughput
19 Citations (Scopus)

Insulator-based dielectrophoresis with β-galactosidase in nanostructured devices

Nakano, A., Camacho-Alanis, F. & Ros, A., Feb 7 2015, In : Analyst. 140, 3, p. 860-868 9 p.

Research output: Contribution to journalArticle

Galactosidases
Electrophoresis
Proteins
Equipment and Supplies
protein
8 Citations (Scopus)

Microfluidic sorting of protein nanocrystals by size for X-ray free-electron laser diffraction

Abdallah, B. G., Zatsepin, N., Roy-Chowdhury, S., Coe, J., Conrad, C. E., Dörner, K., Sierra, R. G., Stevenson, H. P., Camacho-Alanis, F., Grant, T. D., Nelson, G., James, D., Calero, G., Wachter, R., Spence, J., Weierstall, U., Fromme, P. & Ros, A., Jul 1 2015, In : Structural Dynamics. 2, 4, 041719.

Research output: Contribution to journalArticle

X ray lasers
Free electron lasers
classifying
Sorting
Microfluidics
6 Citations (Scopus)

Polarizability of Six-Helix Bundle and Triangle DNA Origami and Their Escape Characteristics from a Dielectrophoretic Trap

Gan, L., Camacho-Alanis, F. & Ros, A., Dec 15 2015, In : Analytical Chemistry. 87, 24, p. 12059-12064 6 p.

Research output: Contribution to journalArticle

DNA
Electrophoresis
Nanoelectronics
Colloids
Charge density
6 Citations (Scopus)

Protein dielectrophoresis and the link to dielectric properties

Camacho-Alanis, F. & Ros, A., Feb 1 2015, In : Bioanalysis. 7, 3, p. 353-371 19 p.

Research output: Contribution to journalArticle

Dielectric Spectroscopy
Dielectric spectroscopy
Electrophoresis
Dielectric properties
Electrochemical impedance spectroscopy
2014
6 Citations (Scopus)

Combined single cell AFM manipulation and TIRFM for probing the molecular stability of multilayer fibrinogen matrices

Christenson, W., Yermolenko, I., Plochberger, B., Camacho-Alanis, F., Ros, A., Ugarova, T. & Ros, R., 2014, In : Ultramicroscopy. 136, p. 211-215 5 p.

Research output: Contribution to journalArticle

fibrinogen
Fibrinogen
manipulators
Multilayers
atomic force microscopy
23 Citations (Scopus)

Insulator-based dielectrophoresis of mitochondria

Luo, J., Abdallah, B. G., Wolken, G. G., Arriaga, E. A. & Ros, A., Mar 1 2014, In : Biomicrofluidics. 8, 2, 21801.

Research output: Contribution to journalArticle

Mitochondria
mitochondria
Electrophoresis
insulators
Lab-On-A-Chip Devices
28 Citations (Scopus)

Selective trapping of single mammalian breast cancer cells by insulator-based dielectrophoresis

Bhattacharya, S., Chao, T. C., Ariyasinghe, N., Ruiz, Y., Lake, D., Ros, R. & Ros, A., 2014, In : Analytical and Bioanalytical Chemistry. 406, 7, p. 1855-1865 11 p.

Research output: Contribution to journalArticle

Electrophoresis
Cells
Breast Neoplasms
Microfluidics
Lab-On-A-Chip Devices
255 Citations (Scopus)

Serial time-resolved crystallography of photosystem II using a femtosecond X-ray laser

Kupitz, C., Basu, S., Grotjohann, I., Fromme, R., Zatsepin, N., Rendek, K. N., Hunter, M. S., Shoeman, R. L., White, T. A., Wang, D., James, D., Yang, J. H., Cobb, D. E., Reeder, B., Sierra, R. G., Liu, H., Barty, A., Aquila, A. L., Deponte, D., Kirian, R. & 39 others, Bari, S., Bergkamp, J. J., Beyerlein, K. R., Bogan, M. J., Caleman, C., Chao, T. C., Conrad, C. E., Davis, K. M., Fleckenstein, H., Galli, L., Hau-Riege, S. P., Kassemeyer, S., Laksmono, H., Liang, M., Lomb, L., Marchesini, S., Martin, A. V., Messerschmidt, M., Milathianaki, D., Nass, K., Ros, A., Roy-Chowdhury, S., Schmidt, K., Seibert, M., Steinbrener, J., Stellato, F., Yan, L., Yoon, C., Moore, T., Moore, A., Pushkar, Y., Williams, G. J., Boutet, S., Doak, R. B., Weierstall, U., Frank, M., Chapman, H. N., Spence, J. & Fromme, P., Sep 11 2014, In : Nature. 513, 7517, p. 261-265 5 p.

Research output: Contribution to journalArticle

Crystallography
Photosystem II Protein Complex
Lasers
X-Rays
Photosynthesis
16 Citations (Scopus)

Temporal and spatial temperature measurement in insulator-based dielectrophoretic devices

Nakano, A., Luo, J. & Ros, A., Jul 1 2014, In : Analytical Chemistry. 86, 13, p. 6516-6524 9 p.

Research output: Contribution to journalArticle

Electrophoresis
Temperature measurement
Temperature
Mitochondria
Joule heating
2013

Bioanalysis Young Investigator Award 2013.

O'Donoghue, A. J., Hua, S., Meyer, B. & Ros, A., Jul 2013, In : Bioanalysis. 5, 13, p. 1617-1621 5 p.

Research output: Contribution to journalArticle

Analytic Chemistry
Analytical Chemistry Techniques
Research Personnel
13 Citations (Scopus)

Crystallization of the large membrane protein complex photosystem i in a microfluidic channel

Abdallah, B. G., Kupitz, C., Fromme, P. & Ros, A., Dec 23 2013, In : ACS Nano. 7, 12, p. 10534-10543 10 p.

Research output: Contribution to journalArticle

Crystallization
Microfluidics
Membrane Proteins
crystallization
membranes
45 Citations (Scopus)

Dielectrophoresis of lambda-DNA using 3D carbon electrodes

Martinez-Duarte, R., Camacho-Alanis, F., Renaud, P. & Ros, A., Apr 2013, In : Electrophoresis. 34, 7, p. 1113-1122 10 p.

Research output: Contribution to journalArticle

Electrophoresis
Electrodes
Carbon
DNA
Theoretical Models
32 Citations (Scopus)

Dielectrophoretic sorting of membrane protein nanocrystals

Abdallah, B. G., Chao, T. C., Kupitz, C., Fromme, P. & Ros, A., Oct 22 2013, In : ACS Nano. 7, 10, p. 9129-9137 9 p.

Research output: Contribution to journalArticle

classifying
Sorting
Nanocrystals
nanocrystals
Membrane Proteins
33 Citations (Scopus)

Mighty small: Observing and modeling individual microbes becomes big science

Kreft, J. U., Plugge, C. M., Grimm, V., Prats, C., Leveau, J. H. J., Banitz, T., Baines, S., Clark, J., Ros, A., Klapper, I., Topping, C. J., Field, A. J., Schuler, A., Litchman, E. & Hellweger, F. L., Nov 5 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 45, p. 18027-18028 2 p.

Research output: Contribution to journalArticle

Microbiological Techniques
Single-Cell Analysis
Biological Models
Microbiology
68 Citations (Scopus)

Protein dielectrophoresis: Advances, challenges, and applications

Nakano, A. & Ros, A., Apr 2013, In : Electrophoresis. 34, 7, p. 1085-1096 12 p.

Research output: Contribution to journalArticle

Electrophoresis
Proteins
Biosensing Techniques
Theoretical Models
Fractionation
14 Citations (Scopus)

Six-helix bundle and triangle DNA origami insulator-based dielectrophoresis

Gan, L., Chao, T. C., Camacho-Alanis, F. & Ros, A., Dec 3 2013, In : Analytical Chemistry. 85, 23, p. 11427-11434 8 p.

Research output: Contribution to journalArticle

Electrophoresis
DNA
Nanoelectronics
Purification
Numerical models
2012
16 Citations (Scopus)

Direct detection of peptides and proteins on a microfluidic platform with MALDI mass spectrometry

Yang, M., Chao, T. C., Nelson, R. & Ros, A., Oct 2012, In : Analytical and Bioanalytical Chemistry. 404, 6-7, p. 1681-1689 9 p.

Research output: Contribution to journalArticle

Microfluidics
Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry
Mass spectrometry
Mass Spectrometry
Mass spectrometers
11 Citations (Scopus)

Microfluidic gel electrophoresis in the undergraduate laboratory applied to food analysis

Chao, T. C., Bhattacharya, S. & Ros, A., Jan 1 2012, In : Journal of Chemical Education. 89, 1, p. 125-129 5 p.

Research output: Contribution to journalArticle

Electrophoresis
Microfluidics
Gels
Polymerase chain reaction
food
33 Citations (Scopus)

Transitioning streaming to trapping in DC insulator-based dielectrophoresis for biomolecules

Camacho-Alanis, F., Gan, L. & Ros, A., Oct 2012, In : Sensors and Actuators, B: Chemical. 173, p. 668-675 8 p.

Research output: Contribution to journalArticle

Biomolecules
Electrophoresis
direct current
trapping
insulators
34 Citations (Scopus)

Tuning direct current streaming dielectrophoresis of proteins

Nakano, A., Camacho-Alanis, F., Chao, T. C. & Ros, A., Jul 18 2012, In : Biomicrofluidics. 6, 3, 034108.

Research output: Contribution to journalArticle

Electrophoresis
Tuning
direct current
tuning
insulators
2011
51 Citations (Scopus)

Immunoglobulin G and bovine serum albumin streaming dielectrophoresis in a microfluidic device

Nakano, A., Chao, T. C., Camacho-Alanis, F. & Ros, A., Sep 2011, In : Electrophoresis. 32, 17, p. 2314-2322 9 p.

Research output: Contribution to journalArticle

Lab-On-A-Chip Devices
Bovine Serum Albumin
Electrophoresis
Microfluidics
Immunoglobulin G
30 Citations (Scopus)

Insulator-based dielectrophoretic single particle and single cancer cell trapping

Bhattacharya, S., Chao, T. C. & Ros, A., Sep 2011, In : Electrophoresis. 32, 18, p. 2550-2558 9 p.

Research output: Contribution to journalArticle

Electrophoresis
Cells
Microfluidics
Neoplasms
Single-Cell Analysis
28 Citations (Scopus)

Physisorbed surface coatings for poly(dimethylsiloxane) and quartz microfluidic devices

Viefhues, M., Manchanda, S., Chao, T. C., Anselmetti, D., Regtmeier, J. & Ros, A., Oct 2011, In : Analytical and Bioanalytical Chemistry. 401, 7, p. 2113-2122 10 p.

Research output: Contribution to journalArticle

Lab-On-A-Chip Devices
Electroosmosis
Quartz
Microfluidics
Coatings
25 Citations (Scopus)

Quantification of pH gradients and implications in insulator-based dielectrophoresis of biomolecules

Gencoglu, A., Camacho-Alanis, F., Nguyen, V. T., Nakano, A., Ros, A. & Minerick, A. R., Sep 2011, In : Electrophoresis. 32, 18, p. 2436-2447 12 p.

Research output: Contribution to journalArticle

Proton-Motive Force
Biomolecules
Microchannels
Electrophoresis
Coloring Agents
2010
40 Citations (Scopus)

Dielectrophoretic trapping and polarizability of DNA: The role of spatial conformation

Regtmeier, J., Eichhorn, R., Bogunovic, L., Ros, A. & Anselmetti, D., Sep 1 2010, In : Analytical Chemistry. 82, 17, p. 7141-7149 9 p.

Research output: Contribution to journalArticle

Conformations
DNA
Superhelical DNA
DNA Vaccines
Molecules
2008
5 Citations (Scopus)

Microfluidics in cell analysis

Ros, A., Feb 2008, In : Analytical and Bioanalytical Chemistry. 390, 3, p. 799-800 2 p.

Research output: Contribution to journalArticle

Microfluidics
Lab-On-A-Chip Devices
Lab-on-a-chip
DNA
Throughput
79 Citations (Scopus)

Microfluidic single-cell analysis of intracellular compounds

Chao, T. C. & Ros, A., 2008, In : Journal of the Royal Society Interface. 5, SUPPL.2

Research output: Contribution to journalArticle

Single-Cell Analysis
Microfluidics
Lab-on-a-chip
Cell proliferation
Dilution
27 Citations (Scopus)

Single cell analysis in full body quartz glass chips with native UV laser-induced fluorescence detection

Greif, D., Galla, L., Ros, A. & Anselmetti, D., Oct 3 2008, In : Journal of Chromatography A. 1206, 1, p. 83-88 6 p.

Research output: Contribution to journalArticle

Single-Cell Analysis
Quartz
Glass
Lasers
Microfluidics
2007
12 Citations (Scopus)

Acceleration of absolute negative mobility

Regtmeier, J., Grauwin, S., Eichhorn, R., Reinmann, P., Anselmetti, D. & Ros, A., Jul 2007, In : Journal of Separation Science. 30, 10, p. 1461-1467 7 p.

Research output: Contribution to journalArticle

Lab-On-A-Chip Devices
Microfluidics
Nonlinear Dynamics
Brownian movement
Sorting
98 Citations (Scopus)

Dielectrophoretic manipulation of DNA: Separation and polarizability

Regtmeier, J., Thanh, T. D., Eichhorn, R., Anselmetti, D. & Ros, A., May 15 2007, In : Analytical Chemistry. 79, 10, p. 3925-3932 8 p.

Research output: Contribution to journalArticle

DNA
Electrophoresis
Superhelical DNA
Gene therapy
Biomolecules
10 Citations (Scopus)

Paradoxical Brownian motion in a microfluidic device: Absolute negative mobility

Eichhorn, R., Ros, A., Regtmeier, J., Tu Duong, T., Reimann, P. & Anselmetti, D., Apr 2007, In : European Physical Journal: Special Topics. 143, 1, p. 159-164 6 p.

Research output: Contribution to journalArticle

Lab-on-a-chip
Thermal noise
microfluidic devices
Brownian movement
thermal noise
18 Citations (Scopus)

Pulsed-field separation of particles in a microfluidic device

Regtmeier, J., Eichhorn, R., Duong, T. T., Reimann, P., Anselmetti, D. & Ros, A., Apr 2007, In : European Physical Journal E. 22, 4, p. 335-340 6 p.

Research output: Contribution to journalArticle

Lab-On-A-Chip Devices
microfluidic devices
Polystyrenes
Microfluidics
Theoretical Models
11 Citations (Scopus)

Systems nanobiology: from quantitative single molecule biophysics to microfluidic-based single cell analysis.

Martini, J., Hellmich, W., Greif, D., Becker, A., Merkle, T., Ros, R., Ros, A., Toensing, K. & Anselmetti, D., 2007, In : Sub-Cellular Biochemistry. 43, p. 301-321 21 p.

Research output: Contribution to journalArticle

Biophysics
Single-Cell Analysis
Microfluidics
Molecules
Gene expression regulation
2006
54 Citations (Scopus)

Bioanalysis in structured microfluidic systems

Ros, A., Hellmich, W., Regtmeier, J., Duong, T. T. & Anselmetti, D., Jul 2006, In : Electrophoresis. 27, 13, p. 2651-2658 8 p.

Research output: Contribution to journalArticle

Lab-On-A-Chip Devices
Microfluidics
Protein Array Analysis
Molecular Dynamics Simulation
Hot Temperature
42 Citations (Scopus)

Improved native UV laser induced fluorescence detection for single cell analysis in poly(dimethylsiloxane) microfluidic devices

Hellmich, W., Greif, D., Pelargus, C., Anselmetti, D. & Ros, A., Oct 20 2006, In : Journal of Chromatography A. 1130, 2 SPEC. ISS., p. 195-200 6 p.

Research output: Contribution to journalArticle

Lab-On-A-Chip Devices
Single-Cell Analysis
Microfluidics
Labels
Lasers
2005
76 Citations (Scopus)

Brownian motion: Absolute negative particle mobility

Ros, A., Eichhorn, R., Regtmeier, J., Duong, T. T., Reimann, P. & Anselmetti, D., Aug 18 2005, In : Nature. 436, 7053, p. 928 1 p.

Research output: Contribution to journalArticle

Brownian motion
particle
98 Citations (Scopus)

Poly(oxyethylene) based surface coatings for poly(dimethylsiloxane) microchannels

Hellmich, W., Regtmeier, J., Duong, T. T., Ros, R., Anselmetti, D. & Ros, A., Aug 2 2005, In : Langmuir. 21, 16, p. 7551-7557 7 p.

Research output: Contribution to journalArticle

Polydimethylsiloxane
microchannels
Microchannels
coatings
Coatings

Single cell analytics for NanoBiology

Anselmetti, D., Griemla, N., Hellmich, W., Leffhalm, K., Ros, A., Ros, R., Sischka, A. & Tönsing, K., 2005, In : Nanobiotechnology. 1, 3, p. 267-270 4 p.

Research output: Contribution to journalArticle

Proteins
Optical tweezers
Microfluidics
Surface structure
Labels
105 Citations (Scopus)

Single cell manipulation, analytics, and label-free protein detection in microfluidic devices for systems nanobiology

Hellmich, W., Pelargus, C., Leffhalm, K., Ros, A. & Anselmetti, D., Oct 2005, In : Electrophoresis. 26, 19, p. 3689-3696 8 p.

Research output: Contribution to journalArticle

Lab-On-A-Chip Devices
Microfluidics
Labels
Proteins
Proteomics
30 Citations (Scopus)

Two-state migration of DNA in a structured microchannel

Streek, M., Schmid, F., Duong, T. T., Anselmetti, D. & Ros, A., Jan 2005, In : Physical Review E - Statistical, Nonlinear, and Soft Matter Physics. 71, 1, 011905.

Research output: Contribution to journalArticle

Microchannel
microchannels
Migration
deoxyribonucleic acid
DNA
2004
51 Citations (Scopus)

Mechanisms of DNA separation in entropic trap arrays: A Brownian dynamics simulation

Streek, M., Schmid, F., Duong, T. T. & Ros, A., Aug 26 2004, In : Journal of Biotechnology. 112, 1-2, p. 79-89 11 p.

Research output: Contribution to journalArticle

Chain length
Constriction
DNA
Equipment and Supplies
Computer simulation