TY - JOUR
T1 - 5β-Dihydrotestosterone is weakly androngenic in the adult Japanese quail (Coturnix coturnix japonica)
AU - Deviche, P.
AU - Bottoni, L.
AU - Balthazart, J.
N1 - Funding Information:
We are indebted to Professor E. Schoffeniels for his continued interest in our work. This study was partially supported by Grant 2.4544.76 from the Fonds de la Recherche Fondamentale Collective to Professor E. Schoffeniels and by a grant from the Belgian FNRS to J. Balthazart. P. Deviche is Senior Research Assistant at the Belgian National Fund for Scientific Research.
PY - 1982/12
Y1 - 1982/12
N2 - Adult male castrated quail received injections of 0 or 2 mg of 5β-dihydrotestosterone (β-DHT) for 14 consecutive days. These treatments were combined with daily injections of 0.1, 0.5, or 1.0 mg testosterone (T). Control birds were injected with the same volume (0.2 ml) of propylene glycol which was the solvent for all steroids. The cloacal gland area and the sexual activity of all birds were repeatedly measured during the period of injections. At the end, the sternotracheal muscles of all males were also weighed. Treatment with T stimulated the cloacal gland growth and increased the sternotracheal muscle weight. β-DHT injections also produced a weak, though quite consistent stimulation of these parameters. The effects of the two steroids were additive, and did not interact with each other. By themselves, β-DHT injections were ineffective on behavior, but they potentiated the stimulating action of 0.5 mg T administration. These results indicate that β-DHT cannot be considered as an inactive steroid in male birds.
AB - Adult male castrated quail received injections of 0 or 2 mg of 5β-dihydrotestosterone (β-DHT) for 14 consecutive days. These treatments were combined with daily injections of 0.1, 0.5, or 1.0 mg testosterone (T). Control birds were injected with the same volume (0.2 ml) of propylene glycol which was the solvent for all steroids. The cloacal gland area and the sexual activity of all birds were repeatedly measured during the period of injections. At the end, the sternotracheal muscles of all males were also weighed. Treatment with T stimulated the cloacal gland growth and increased the sternotracheal muscle weight. β-DHT injections also produced a weak, though quite consistent stimulation of these parameters. The effects of the two steroids were additive, and did not interact with each other. By themselves, β-DHT injections were ineffective on behavior, but they potentiated the stimulating action of 0.5 mg T administration. These results indicate that β-DHT cannot be considered as an inactive steroid in male birds.
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U2 - 10.1016/0016-6480(82)90176-9
DO - 10.1016/0016-6480(82)90176-9
M3 - Article
C2 - 7160608
AN - SCOPUS:0020396284
SN - 0016-6480
VL - 48
SP - 421
EP - 424
JO - General and Comparative Endocrinology
JF - General and Comparative Endocrinology
IS - 4
ER -