Wireless neural recording with single low-power integrated circuit

Reid R. Harrison, Ryan J. Kier, Cynthia A. Chestek, Vikash Gilja, Paul Nuyujukian, Stephen Ryu, Bradley Greger, Florian Solzbacher, Krishna V. Shenoy

Research output: Contribution to journalArticle

146 Scopus citations


We present benchtop and in vivo experimental results from an integrated circuit designed for wireless implantable neural recording applications. The chip, which was fabricated in a commercially available 0.6-μm 2P3M BiCMOS process, contains 100 amplifiers, a 10-bit analog-to-digital converter (ADC), 100 threshold-based spike detectors, and a 902-928 MHz frequency-shift-keying (FSK) transmitter. Neural signals from a selected amplifier are sampled by the ADC at 15.7 kSps and telemetered over the FSK wireless data link. Power, clock, and command signals are sent to the chip wirelessly over a 2.765-MHz inductive (coil-to-coil) link. The chip is capable of operating with only two off-chip components: a power/command receiving coil and a 100-nF capacitor.

Original languageEnglish (US)
Pages (from-to)322-329
Number of pages8
JournalIEEE Transactions on Neural Systems and Rehabilitation Engineering
Issue number4
StatePublished - Aug 1 2009



  • Brain-machine interface (BMI)
  • Low power
  • Neural prosthetics
  • Telemetry
  • Wireless

ASJC Scopus subject areas

  • Internal Medicine
  • Neuroscience(all)
  • Biomedical Engineering

Cite this

Harrison, R. R., Kier, R. J., Chestek, C. A., Gilja, V., Nuyujukian, P., Ryu, S., Greger, B., Solzbacher, F., & Shenoy, K. V. (2009). Wireless neural recording with single low-power integrated circuit. IEEE Transactions on Neural Systems and Rehabilitation Engineering, 17(4), 322-329. https://doi.org/10.1109/TNSRE.2009.2023298