Waveform processing for protein multi-alignment by mapping location, structure and property function attributes

Brian O'Donnell, Alexander Maurer, Antonia Papandreou-Suppappola

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

We propose a pairwise protein structure alignment approach based on a joint similarity measure of multiple protein attributes. We map information on a protein's sequence location, structure and characteristic properties onto a highly-localized three-dimensional Gaussian waveform. By allowing the waveform to undergo unique transformations in the time-frequency plane, we allocate distinct parameters to represent the different attributes. Protein matching by expanding the mapped waveforms using appropriately designed basis waveform functions provides a similarity measure to encompass the multiple attributes. Simulations using data from a database demonstrate the performance of the joint alignment approach to infer relationships between proteins.

Original languageEnglish (US)
Title of host publicationConference Record - Asilomar Conference on Signals, Systems and Computers
PublisherIEEE Computer Society
Pages248-252
Number of pages5
ISBN (Print)9781479923908
DOIs
StatePublished - 2013
Event2013 47th Asilomar Conference on Signals, Systems and Computers - Pacific Grove, CA, United States
Duration: Nov 3 2013Nov 6 2013

Other

Other2013 47th Asilomar Conference on Signals, Systems and Computers
CountryUnited States
CityPacific Grove, CA
Period11/3/1311/6/13

Fingerprint

Proteins
Processing

ASJC Scopus subject areas

  • Computer Networks and Communications
  • Signal Processing

Cite this

O'Donnell, B., Maurer, A., & Papandreou-Suppappola, A. (2013). Waveform processing for protein multi-alignment by mapping location, structure and property function attributes. In Conference Record - Asilomar Conference on Signals, Systems and Computers (pp. 248-252). [6810270] IEEE Computer Society. https://doi.org/10.1109/ACSSC.2013.6810270

Waveform processing for protein multi-alignment by mapping location, structure and property function attributes. / O'Donnell, Brian; Maurer, Alexander; Papandreou-Suppappola, Antonia.

Conference Record - Asilomar Conference on Signals, Systems and Computers. IEEE Computer Society, 2013. p. 248-252 6810270.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

O'Donnell, B, Maurer, A & Papandreou-Suppappola, A 2013, Waveform processing for protein multi-alignment by mapping location, structure and property function attributes. in Conference Record - Asilomar Conference on Signals, Systems and Computers., 6810270, IEEE Computer Society, pp. 248-252, 2013 47th Asilomar Conference on Signals, Systems and Computers, Pacific Grove, CA, United States, 11/3/13. https://doi.org/10.1109/ACSSC.2013.6810270
O'Donnell B, Maurer A, Papandreou-Suppappola A. Waveform processing for protein multi-alignment by mapping location, structure and property function attributes. In Conference Record - Asilomar Conference on Signals, Systems and Computers. IEEE Computer Society. 2013. p. 248-252. 6810270 https://doi.org/10.1109/ACSSC.2013.6810270
O'Donnell, Brian ; Maurer, Alexander ; Papandreou-Suppappola, Antonia. / Waveform processing for protein multi-alignment by mapping location, structure and property function attributes. Conference Record - Asilomar Conference on Signals, Systems and Computers. IEEE Computer Society, 2013. pp. 248-252
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