TY - JOUR
T1 - Walking performance in adolescents and young adults with Down syndrome
T2 - the role of obesity and sleep problems
AU - Chen, C. C.J.J.
AU - Ringenbach, Shannon
N1 - Publisher Copyright:
© 2018 MENCAP and International Association of the Scientific Study of Intellectual and Developmental Disabilities and John Wiley & Sons Ltd
PY - 2018/4
Y1 - 2018/4
N2 - Background: High prevalence of obesity and features of obstructive sleep apnea (OSA) are major health issues in individuals with Down syndrome (DS), and both may also affect adversely on their daily activities. Further, lower levels of physical work capacity (PWC) have been reported in this population compared to their peers with intellectual disabilities. However, no study examines the relationships between obesity and sleep problems with PWC in individuals with DS. Thus, this study investigated the influence of body mass index (BMI) and different types of sleep problems on PWC in adolescents and young adults with DS (14–31 years). Methods: The incremental treadmill walking trial was used to assess PWC. Results: The negative associations were indicated between BMI and walking steps (p =.03) as well as features with OSA and walking steps (p =.04). Thus, BMI and OSA were included in the regression analysis to estimate the walking steps achieved during walking trials. In addition, Bland-Altman plots demonstrated no overestimation and underestimation of variability in the difference between actual and estimated walking steps developed by using BMI and OSA. Conclusions: Obesity and sleep problem are potentially detrimental to walking performance (i.e., fewer walking steps) in individuals with DS. Thus, individuals with DS may adopt a slow walk speed due to the increased balance deficits and physical fatigue that result from obesity and sleep fragmentation, respectively. Exercise interventions, which have the potential to reduce obesity and OSA, are recommended to improve the accomplishment of PWC in individuals with DS.
AB - Background: High prevalence of obesity and features of obstructive sleep apnea (OSA) are major health issues in individuals with Down syndrome (DS), and both may also affect adversely on their daily activities. Further, lower levels of physical work capacity (PWC) have been reported in this population compared to their peers with intellectual disabilities. However, no study examines the relationships between obesity and sleep problems with PWC in individuals with DS. Thus, this study investigated the influence of body mass index (BMI) and different types of sleep problems on PWC in adolescents and young adults with DS (14–31 years). Methods: The incremental treadmill walking trial was used to assess PWC. Results: The negative associations were indicated between BMI and walking steps (p =.03) as well as features with OSA and walking steps (p =.04). Thus, BMI and OSA were included in the regression analysis to estimate the walking steps achieved during walking trials. In addition, Bland-Altman plots demonstrated no overestimation and underestimation of variability in the difference between actual and estimated walking steps developed by using BMI and OSA. Conclusions: Obesity and sleep problem are potentially detrimental to walking performance (i.e., fewer walking steps) in individuals with DS. Thus, individuals with DS may adopt a slow walk speed due to the increased balance deficits and physical fatigue that result from obesity and sleep fragmentation, respectively. Exercise interventions, which have the potential to reduce obesity and OSA, are recommended to improve the accomplishment of PWC in individuals with DS.
KW - intellectual disabilities
KW - obesity
KW - physical work capacity
KW - sleep disorders
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U2 - 10.1111/jir.12474
DO - 10.1111/jir.12474
M3 - Article
C2 - 29484778
AN - SCOPUS:85043571373
SN - 0964-2633
VL - 62
SP - 339
EP - 348
JO - Journal of Intellectual Disability Research
JF - Journal of Intellectual Disability Research
IS - 4
ER -