Variation in CCL3L1 copy number in rhesus macaques (Macaca mulatta)

Patrick L. Taormina, Jessica A. Satkoski Trask, David G. Smith, Sreetharan Kanthaswamy

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

We used real-time quantitative PCR (qPCR) methodology to examine copy number variation (CNV) of the CCL3L1 gene among pure Indian-origin, pure Chinese-origin, and hybrid Indian-Chinese rhesus macaques (Macaca mulatta). CNV among purebred macaques fell within expected ranges, with Indian macaques having lower copy numbers than those of Chinese macaques. Compared with the purebred macaques, Indian-Chinese hybrid rhesus macaques showed much greater variance in copy number and an intermediate average copy number. Copy numbers of CCL3L1 in rhesus macaque trios (sire, dam, and offspring) were consistent with Mendelian inheritance.

Original languageEnglish (US)
Pages (from-to)218-224
Number of pages7
JournalComparative Medicine
Volume62
Issue number3
StatePublished - Jun 2012

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • veterinary(all)

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  • Cite this

    Taormina, P. L., Satkoski Trask, J. A., Smith, D. G., & Kanthaswamy, S. (2012). Variation in CCL3L1 copy number in rhesus macaques (Macaca mulatta). Comparative Medicine, 62(3), 218-224.