Validity and reliablity of the newly translated Hellenic Neuropsychiatric Inventory (H-NPI) applied to Greek outpatients with Alzheimer's disease: A study of disturbing behaviors among referrals to a memory clinic

Antonis M. Politis, Lawrence S. Mayer, Maria Passa, Antonis Maillis, Constantine G. Lyketsos

Research output: Contribution to journalArticle

46 Scopus citations

Abstract

Context. No rating scales of the neuropsychiatric symptoms of patients with dementia and Alzheimer's disease (AD) have previously been developed or translated. Objectives. To develop a Hellenic translation of the Neuropsychiatric Inventory (NPI), to evaluate it's reliability and validity, and to compare NPI results in Greek patients referred to a neuropsychiatry clinic for either of two reasons: disturbing behaviors evoking embarrassment and disturbing behaviors evoking fear in the caregiver. Methods. The Hellenic translations of the NPI, Brief Psychiatric Rating Scale (BPRS), and Emotional Distress Scale (EDS) were compared in evaluating 29 consecutive referrals of patients with AD. Results. The Hellenic NPI (H-NPI) demonstrated a high degree of internal consistency reliability, and of concurrent validity when compared to the BPRS or the EDS. Patients referred for behaviors evoking embarrassment presented with higher scores on NPI ratings of apathy. However, patients referred for behaviors evoking fear presented with higher scores on NPI ratings of aggression and irritability. Conclusions. These results indicate that the H-NPI is a reliable instrument, able to detect differences in clinically referred groups of AD patients.

Original languageEnglish (US)
Pages (from-to)203-208
Number of pages6
JournalInternational Journal of Geriatric Psychiatry
Volume19
Issue number3
DOIs
StatePublished - Mar 1 2004

Keywords

  • Alzheimer's disease
  • Apathy
  • Behavior disturbance
  • Brief Psychiatric Rating Scale (BPRS)
  • Dementia
  • Neuropsychiatric Inventory (NPI)

ASJC Scopus subject areas

  • Geriatrics and Gerontology
  • Psychiatry and Mental health

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