Validity and reliablity of the newly translated Hellenic Neuropsychiatric Inventory (H-NPI) applied to Greek outpatients with Alzheimer's disease: A study of disturbing behaviors among referrals to a memory clinic

Antonis M. Politis; Lawrence S. Mayer; Maria Passa; Antonis Maillis; Constantine G. Lyketsos

doi:10.1002/gps.1045

Validity and reliablity of the newly translated Hellenic Neuropsychiatric Inventory (H-NPI) applied to Greek outpatients with Alzheimer's disease: A study of disturbing behaviors among referrals to a memory clinic

Antonis M. Politis, Lawrence S. Mayer, Maria Passa, Antonis Maillis, Constantine G. Lyketsos

Arizona State University

Research output: Contribution to journal › Article › peer-review

71 Scopus citations

Abstract

Context. No rating scales of the neuropsychiatric symptoms of patients with dementia and Alzheimer's disease (AD) have previously been developed or translated. Objectives. To develop a Hellenic translation of the Neuropsychiatric Inventory (NPI), to evaluate it's reliability and validity, and to compare NPI results in Greek patients referred to a neuropsychiatry clinic for either of two reasons: disturbing behaviors evoking embarrassment and disturbing behaviors evoking fear in the caregiver. Methods. The Hellenic translations of the NPI, Brief Psychiatric Rating Scale (BPRS), and Emotional Distress Scale (EDS) were compared in evaluating 29 consecutive referrals of patients with AD. Results. The Hellenic NPI (H-NPI) demonstrated a high degree of internal consistency reliability, and of concurrent validity when compared to the BPRS or the EDS. Patients referred for behaviors evoking embarrassment presented with higher scores on NPI ratings of apathy. However, patients referred for behaviors evoking fear presented with higher scores on NPI ratings of aggression and irritability. Conclusions. These results indicate that the H-NPI is a reliable instrument, able to detect differences in clinically referred groups of AD patients.

Original language	English (US)
Pages (from-to)	203-208
Number of pages	6
Journal	International Journal of Geriatric Psychiatry
Volume	19
Issue number	3
DOIs	https://doi.org/10.1002/gps.1045
State	Published - Mar 1 2004

Keywords

Alzheimer's disease
Apathy
Behavior disturbance
Brief Psychiatric Rating Scale (BPRS)
Dementia
Neuropsychiatric Inventory (NPI)

ASJC Scopus subject areas

Geriatrics and Gerontology
Psychiatry and Mental health

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Politis, A. M., Mayer, L. S., Passa, M., Maillis, A., & Lyketsos, C. G. (2004). Validity and reliablity of the newly translated Hellenic Neuropsychiatric Inventory (H-NPI) applied to Greek outpatients with Alzheimer's disease: A study of disturbing behaviors among referrals to a memory clinic. International Journal of Geriatric Psychiatry, 19(3), 203-208. https://doi.org/10.1002/gps.1045

Validity and reliablity of the newly translated Hellenic Neuropsychiatric Inventory (H-NPI) applied to Greek outpatients with Alzheimer's disease : A study of disturbing behaviors among referrals to a memory clinic. / Politis, Antonis M.; Mayer, Lawrence S.; Passa, Maria et al.

In: International Journal of Geriatric Psychiatry, Vol. 19, No. 3, 01.03.2004, p. 203-208.

Research output: Contribution to journal › Article › peer-review

Politis, AM, Mayer, LS, Passa, M, Maillis, A & Lyketsos, CG 2004, 'Validity and reliablity of the newly translated Hellenic Neuropsychiatric Inventory (H-NPI) applied to Greek outpatients with Alzheimer's disease: A study of disturbing behaviors among referrals to a memory clinic', International Journal of Geriatric Psychiatry, vol. 19, no. 3, pp. 203-208. https://doi.org/10.1002/gps.1045

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abstract = "Context. No rating scales of the neuropsychiatric symptoms of patients with dementia and Alzheimer's disease (AD) have previously been developed or translated. Objectives. To develop a Hellenic translation of the Neuropsychiatric Inventory (NPI), to evaluate it's reliability and validity, and to compare NPI results in Greek patients referred to a neuropsychiatry clinic for either of two reasons: disturbing behaviors evoking embarrassment and disturbing behaviors evoking fear in the caregiver. Methods. The Hellenic translations of the NPI, Brief Psychiatric Rating Scale (BPRS), and Emotional Distress Scale (EDS) were compared in evaluating 29 consecutive referrals of patients with AD. Results. The Hellenic NPI (H-NPI) demonstrated a high degree of internal consistency reliability, and of concurrent validity when compared to the BPRS or the EDS. Patients referred for behaviors evoking embarrassment presented with higher scores on NPI ratings of apathy. However, patients referred for behaviors evoking fear presented with higher scores on NPI ratings of aggression and irritability. Conclusions. These results indicate that the H-NPI is a reliable instrument, able to detect differences in clinically referred groups of AD patients.",

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AB - Context. No rating scales of the neuropsychiatric symptoms of patients with dementia and Alzheimer's disease (AD) have previously been developed or translated. Objectives. To develop a Hellenic translation of the Neuropsychiatric Inventory (NPI), to evaluate it's reliability and validity, and to compare NPI results in Greek patients referred to a neuropsychiatry clinic for either of two reasons: disturbing behaviors evoking embarrassment and disturbing behaviors evoking fear in the caregiver. Methods. The Hellenic translations of the NPI, Brief Psychiatric Rating Scale (BPRS), and Emotional Distress Scale (EDS) were compared in evaluating 29 consecutive referrals of patients with AD. Results. The Hellenic NPI (H-NPI) demonstrated a high degree of internal consistency reliability, and of concurrent validity when compared to the BPRS or the EDS. Patients referred for behaviors evoking embarrassment presented with higher scores on NPI ratings of apathy. However, patients referred for behaviors evoking fear presented with higher scores on NPI ratings of aggression and irritability. Conclusions. These results indicate that the H-NPI is a reliable instrument, able to detect differences in clinically referred groups of AD patients.

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Validity and reliablity of the newly translated Hellenic Neuropsychiatric Inventory (H-NPI) applied to Greek outpatients with Alzheimer's disease: A study of disturbing behaviors among referrals to a memory clinic

Abstract

Keywords

ASJC Scopus subject areas

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