Ultrasound imaging media layer texture analysis of the carotid artery

C. P. Loizou, M. Pantziaris, A. Nicolaides, Andreas Spanias, M. S. Pattichis, C. S. Pattichis

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The intima-media thickness (IMT) of the common carotid artery (CCA) is widely used as an early indicator of cardiovascular disease (CVD). It was proposed but not thoroughly investigated that the media layer (ML), its composition and texture, may be indicative for identifying the risk of stroke and differentiating between patients of high and low risk. In this study we investigate the usefulness of texture analysis of the ML of the CCA. The study was performed on 100 longitudinal ultrasound images acquired from asymptomatic subjects at risk of atherosclerosis. The images were separated into three different age groups, namely below 50, 50 to 60, and above 60 years old. A total of 61 different texture features were extracted from the intima-media complex (IMC), ML and the intima layer (IL). The IMC and ML were segmented manually by a neurovascular expert and automatically by a snakes segmentation system. It was shown that texture features extracted from the IL, ML and IMC are significantly different (mean, gray scale median (GSM), standard deviation, contrast, difference variance, periodicity) and that some of them can be associated with the increase (difference variance, entropy) or decrease (GSM) of patient's age. It was also shown that the GSM of the ML falls linearly with increasing ML thickness (MLT) and with increasing age. Further research on more subjects is required for estimating other features that may provide information for patients at risk of stroke.

Original languageEnglish (US)
Title of host publication8th IEEE International Conference on BioInformatics and BioEngineering, BIBE 2008
DOIs
StatePublished - Dec 1 2008
Event8th IEEE International Conference on BioInformatics and BioEngineering, BIBE 2008 - Athens, Greece
Duration: Oct 8 2008Oct 10 2008

Publication series

Name8th IEEE International Conference on BioInformatics and BioEngineering, BIBE 2008

Other

Other8th IEEE International Conference on BioInformatics and BioEngineering, BIBE 2008
CountryGreece
CityAthens
Period10/8/0810/10/08

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering

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    Loizou, C. P., Pantziaris, M., Nicolaides, A., Spanias, A., Pattichis, M. S., & Pattichis, C. S. (2008). Ultrasound imaging media layer texture analysis of the carotid artery. In 8th IEEE International Conference on BioInformatics and BioEngineering, BIBE 2008 [4696801] (8th IEEE International Conference on BioInformatics and BioEngineering, BIBE 2008). https://doi.org/10.1109/BIBE.2008.4696801