Ultrasonic cardiac pacing in the porcine model

Bruce C. Towe, Raymond Rho

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Periodic pulses of intense ultrasound energy at 70 kHz with 5-ms duration at 3 MPa SPL applied to the exposed pig myocardium at physiologic rhythms were observed to produce cardiac pacing. Ten animals were successfully paced at pulse width and energy conditions above a certain threshold. Sigmoid strength-duration curves characterizing ultrasound's effectiveness in pacing were observed to resemble those of electrical stimulation. We suggest that bioelectrical stimulatory effects of ultrasound on the heart are a radiation pressure effect and a manifestation of the known myocyte sensitivity to stretch.

Original languageEnglish (US)
Article number1643417
Pages (from-to)1446-1448
Number of pages3
JournalIEEE Transactions on Biomedical Engineering
Volume53
Issue number7
DOIs
StatePublished - Jul 2006

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Ultrasonics
Pressure effects
Animals
Radiation

Keywords

  • Radiation pressure stimulation
  • Ultrasonic pacing
  • Ultrasound bioelectric stimulation

ASJC Scopus subject areas

  • Biomedical Engineering

Cite this

Ultrasonic cardiac pacing in the porcine model. / Towe, Bruce C.; Rho, Raymond.

In: IEEE Transactions on Biomedical Engineering, Vol. 53, No. 7, 1643417, 07.2006, p. 1446-1448.

Research output: Contribution to journalArticle

Towe, Bruce C. ; Rho, Raymond. / Ultrasonic cardiac pacing in the porcine model. In: IEEE Transactions on Biomedical Engineering. 2006 ; Vol. 53, No. 7. pp. 1446-1448.
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