Two-photon absorbing block copolymer as a nanocarrier for porphyrin

Energy transfer and singlet oxygen generation in micellar aqueous solution

Ching Yi Chen, Yanqing Tian, Yen Ju Cheng, A. Cody Young, Jae Won Ka, Alex K Y Jen

Research output: Contribution to journalArticle

63 Citations (Scopus)

Abstract

A novel amphiphilic water-soluble 2PA-chromophore-containing block copolymer was designed and synthesized. Micelles (nanostructures) were generated in the aqueous solution using the block copolymer and characterized using dynamic light scattering (DLS) and atomic force microscopy (AFM). We demonstrated that hydrophobic porphyrin could be incorporated into aqueous solution with the assistance of micelles. The results from DLS showed that the average diameters are in the range of 59-77 nm. Efficient energy transfer (as high as 96%) from the 2PA chromophore to porphyrin was observed in micellar aqueous solution even though the donor and acceptor were not covalently bonded. Furthermore, the energy transfer contributes to the efficient generation of the singlet oxygen (by a factor of 2.6 at 800 nm) from the porphyrin guest molecules.

Original languageEnglish (US)
Pages (from-to)7220-7221
Number of pages2
JournalJournal of the American Chemical Society
Volume129
Issue number23
DOIs
StatePublished - Jun 13 2007
Externally publishedYes

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Singlet Oxygen
Energy Transfer
Porphyrins
Photons
Energy transfer
Block copolymers
Micelles
Dynamic light scattering
Chromophores
Oxygen
Nanostructures
Atomic Force Microscopy
Atomic force microscopy
Molecules
Water
Dynamic Light Scattering

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Two-photon absorbing block copolymer as a nanocarrier for porphyrin : Energy transfer and singlet oxygen generation in micellar aqueous solution. / Chen, Ching Yi; Tian, Yanqing; Cheng, Yen Ju; Young, A. Cody; Ka, Jae Won; Jen, Alex K Y.

In: Journal of the American Chemical Society, Vol. 129, No. 23, 13.06.2007, p. 7220-7221.

Research output: Contribution to journalArticle

Chen, Ching Yi ; Tian, Yanqing ; Cheng, Yen Ju ; Young, A. Cody ; Ka, Jae Won ; Jen, Alex K Y. / Two-photon absorbing block copolymer as a nanocarrier for porphyrin : Energy transfer and singlet oxygen generation in micellar aqueous solution. In: Journal of the American Chemical Society. 2007 ; Vol. 129, No. 23. pp. 7220-7221.
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AU - Young, A. Cody

AU - Ka, Jae Won

AU - Jen, Alex K Y

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