In this paper, the problem of informed-transmitter cooperative MIMO communications is addressed. The informed-transmitter link assumes that the distributed transmit nodes have access to channel state information. The channel state information includes the channel between the transmit and receive antenna arrays and a statistical model for interference impinging upon the receive array. In principle, the channel will have resolvable delay spread. In addition, because the distributed sets of nodes do not have a common local oscillator and move independently, the receiving set of nodes may observe resolvable independent frequency offsets and frequency spread from each of the transmit nodes. To compensate for this doubly dispersive channel, a space-time-frequency channel estimate is constructed. The frequency components of the channel estimate enable improved channel prediction capabilities. Space-time-frequency transmit adaptive processing approaches are developed. These techniques are demonstrated in simulation.