Transmission of the Ambystoma tigrinum virus to alternative hosts

J. K. Jancovich, E. W. Davidson, A. Seiler, Bertram Jacobs, James Collins

Research output: Contribution to journalArticlepeer-review

62 Scopus citations

Abstract

Ambystoma tigrinum virus (ATV) is a lethal virus originally isolated from Sonora tiger salamanders Ambystoma tigrinum stebbinsi in the San Rafael Valley in southern Arizona. USA. ATV is implicated in several salamander epizootics. We attempted to transmit ATV experimentally to fish and amphibians by injection, water bath exposure, or feeding to test whether ATV can cause clinical signs of infection or be recovered from exposed individuals that do not show clinical signs. Cell culture and polymerase chain reaction of the viral major capsid protein gene were used for viral detection. Salamanders and newts became infected with ATV and the virus was recovered from these animals, but virus could not be recovered from any of the frogs or fish tested. These results suggest that ATV may only infect urodeles and that fish and frogs may not be susceptible to ATV infection.

Original languageEnglish (US)
Pages (from-to)159-163
Number of pages5
JournalDiseases of Aquatic Organisms
Volume46
Issue number3
DOIs
StatePublished - Oct 8 2001

Keywords

  • Amphibian decline
  • Cell culture
  • Fish
  • Frog
  • Polymerase chain reaction
  • Ranavirus
  • Salamander

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Aquatic Science

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