Transmission dynamics of the amphibian ranavirus Ambystoma tigrinum virus

J. L. Brunner, D. M. Schock, James Collins

Research output: Contribution to journalArticle

64 Citations (Scopus)

Abstract

Transmission is central to pathogen fitness and strongly influences the impact of pathogens on host populations. Particularly important to transmission dynamics is the distinction between direct transmission requiring close physical contact (e.g. bumping, fighting, or coughing) and indirect transmission from environmental sources such as contaminated substrates. We present data from 4 experiments addressing the form, routes, and timing of transmission of Ambystoma tigrinum virus (ATV) among tiger salamanders Ambystoma tigrinum nebulosum. Our data suggest that ATV is efficiently transmitted by direct interactions between live animals (bumping, biting and cannibalism) as well as by necrophagy and indirectly via water and fomites. Determining which form of transmission is most important in nature is essential for understanding transmission at the population level. Our experiments also revealed an important temporal aspect of infectiousness: larval salamanders become infectious soon after exposure to ATV and their propensity to infect others increases with time. These results begin to clarify the mechanisms and dynamics of ATV transmission and lead to key questions that need to be addressed in future research.

Original languageEnglish (US)
Pages (from-to)87-95
Number of pages9
JournalDiseases of Aquatic Organisms
Volume77
Issue number2
DOIs
StatePublished - Sep 14 2007

Fingerprint

Ambystoma tigrinum virus
Ranavirus
amphibian
amphibians
virus
necrophagy
pathogen
fomites
Ambystoma tigrinum
Ambystoma
pathogens
cannibalism
virus transmission
fighting
salamanders and newts
fitness
experiment
substrate
animal
animals

Keywords

  • Ambystoma tigrinum virus
  • ATV
  • Iridoviridae
  • Ranavirus
  • Tiger salamander
  • Transmission

ASJC Scopus subject areas

  • Aquatic Science
  • Ecology

Cite this

Transmission dynamics of the amphibian ranavirus Ambystoma tigrinum virus. / Brunner, J. L.; Schock, D. M.; Collins, James.

In: Diseases of Aquatic Organisms, Vol. 77, No. 2, 14.09.2007, p. 87-95.

Research output: Contribution to journalArticle

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