Translocation of single-stranded DNA through single-walled carbon nanotubes

Haitao Liu, Jin He, Jinyao Tang, Hao Liu, Pei Pang, Di Cao, Predrag Krstic, Sony Joseph, Stuart Lindsay, Colin Nuckolls

Research output: Contribution to journalArticle

217 Citations (Scopus)

Abstract

We report the fabrication of devices in which one single-walled carbon nanotube spans a barrier between two fluid reservoirs, enabling direct electrical measurement of ion transport through the tube. A fraction of the tubes pass anomalously high ionic currents. Electrophoretic transport of small single-stranded DNA oligomers through these tubes is marked by large transient increases in ion current and was confirmed by polymerase chain reaction analysis. Each current pulse contains about 107 charges, an enormous amplification of the translocated charge. Carbon nanotubes simplify the construction of nanopores, permit new types of electrical measurements, and may open avenues for control of DNA translocation.

Original languageEnglish (US)
Pages (from-to)64-67
Number of pages4
JournalScience
Volume327
Issue number5961
DOIs
StatePublished - Jan 1 2010

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Carbon Nanotubes
Single-Stranded DNA
Nanopores
Ion Transport
Ions
Equipment and Supplies
Polymerase Chain Reaction
DNA

ASJC Scopus subject areas

  • General

Cite this

Liu, H., He, J., Tang, J., Liu, H., Pang, P., Cao, D., ... Nuckolls, C. (2010). Translocation of single-stranded DNA through single-walled carbon nanotubes. Science, 327(5961), 64-67. https://doi.org/10.1126/science.1181799

Translocation of single-stranded DNA through single-walled carbon nanotubes. / Liu, Haitao; He, Jin; Tang, Jinyao; Liu, Hao; Pang, Pei; Cao, Di; Krstic, Predrag; Joseph, Sony; Lindsay, Stuart; Nuckolls, Colin.

In: Science, Vol. 327, No. 5961, 01.01.2010, p. 64-67.

Research output: Contribution to journalArticle

Liu, H, He, J, Tang, J, Liu, H, Pang, P, Cao, D, Krstic, P, Joseph, S, Lindsay, S & Nuckolls, C 2010, 'Translocation of single-stranded DNA through single-walled carbon nanotubes', Science, vol. 327, no. 5961, pp. 64-67. https://doi.org/10.1126/science.1181799
Liu H, He J, Tang J, Liu H, Pang P, Cao D et al. Translocation of single-stranded DNA through single-walled carbon nanotubes. Science. 2010 Jan 1;327(5961):64-67. https://doi.org/10.1126/science.1181799
Liu, Haitao ; He, Jin ; Tang, Jinyao ; Liu, Hao ; Pang, Pei ; Cao, Di ; Krstic, Predrag ; Joseph, Sony ; Lindsay, Stuart ; Nuckolls, Colin. / Translocation of single-stranded DNA through single-walled carbon nanotubes. In: Science. 2010 ; Vol. 327, No. 5961. pp. 64-67.
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