Toward homochiral protocells in noncatalytic peptide systems

Marcelo Gleiser, Sara Walker

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

The activation-polymerization-epimerization-depolymerization (APED) model of Plasson et al. has recently been proposed as a mechanism for the evolution of homochirality on prebiotic Earth. The dynamics of the APED model in two-dimensional spatially-extended systems is investigated for various realistic reaction parameters. It is found that the APED system allows for the formation of isolated homochiral proto-domains surrounded by a racemate. A diffusive slowdown of the APED network induced, for example, through tidal motion or evaporating pools and lagoons leads to the stabilization of homochiral bounded structures as expected in the first self-assembled protocells.

Original languageEnglish (US)
Pages (from-to)479-493
Number of pages15
JournalOrigins of Life and Evolution of Biospheres
Volume39
Issue number5
DOIs
StatePublished - Sep 2009
Externally publishedYes

Fingerprint

Artificial Cells
depolymerization
polymerization
Polymerization
peptide
peptides
activation
Peptides
lagoons
Prebiotics
prebiotics
lagoon
stabilization

Keywords

  • Abiogenesis
  • Homochirality
  • Prebiotic chemistry
  • Proto-cells
  • Protometabolism

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Space and Planetary Science
  • Medicine(all)

Cite this

Toward homochiral protocells in noncatalytic peptide systems. / Gleiser, Marcelo; Walker, Sara.

In: Origins of Life and Evolution of Biospheres, Vol. 39, No. 5, 09.2009, p. 479-493.

Research output: Contribution to journalArticle

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