Toward an objective method to classify tremor dominant and postural instability and gait difficulty subtypes of Parkinson’s disease: A pilot study

Saba Rezvanian, Thurmon Lockhart, Christopher Frames, Rahul Soangra

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Abstract

Discriminating the two subtypes of tremor dominant (TD) and postural instability/gait difficulty (PIGD) in Parkinson’s disease (PD) at early stage is highly valuable and crucial for progression treatment of disease for caregivers. However, there is no objective method or a subtype-specific biomarker yet available for identifying these two subtypes. A computational approach in frequency domain could be a good candidate to introduce biomarker since PD tremor had frequency range of 3-7 Hz. By using frequency component of the whole body Center Of Pressure (COP) signal, we propose a ratio between high and low frequency range. To evaluate this ratio, COP data of ten PD patients were utilized. The results suggest that identifying PD subtypes is attainable by using the frequency information of COP signals.

Original languageEnglish (US)
Title of host publication54th Annual Rocky Mountain Bioengineering Symposium, RMBS 2017 and 54th International ISA Biomedical Sciences Instrumentation Symposium 2017
PublisherInternational Society of Automation (ISA)
Volume2017-March
ISBN (Electronic)9781945541193
StatePublished - Jan 1 2017
Event54th Annual Rocky Mountain Bioengineering Symposium, RMBS 2017 and 54th International ISA Biomedical Sciences Instrumentation Symposium 2017 - Denver, United States
Duration: Mar 31 2017Apr 1 2017

Other

Other54th Annual Rocky Mountain Bioengineering Symposium, RMBS 2017 and 54th International ISA Biomedical Sciences Instrumentation Symposium 2017
CountryUnited States
CityDenver
Period3/31/174/1/17

Keywords

  • Center of pressure
  • Fourier Transform
  • Gait difficulty
  • Parkinson’s disease
  • Postural instability
  • Tremor dominant

ASJC Scopus subject areas

  • Bioengineering
  • Instrumentation
  • Biotechnology
  • Biomedical Engineering

Fingerprint Dive into the research topics of 'Toward an objective method to classify tremor dominant and postural instability and gait difficulty subtypes of Parkinson’s disease: A pilot study'. Together they form a unique fingerprint.

Cite this