Threshold logic gene regulatory networks

Tejaswi Gowda, Samuel Leshner, Sarma Vrudhula, Seungchan Kim

Research output: Chapter in Book/Report/Conference proceedingConference contribution

5 Scopus citations

Abstract

Gene regulation is an important modeling problem in biology. The deluge of data generated by improved techniques of gene sequencing will not be of much use until we develop accurate and efficient gene regulatory network (GRN) models. In this paper a novel threshold logic gene regulatory model is proposed. This model has been demonstrated to be powerful enough to explain gene interaction and cellular processes. A novel programmable hardware implementation to speed up the gene network simulation is presented. Some insights into the extension of this model are provided.

Original languageEnglish (US)
Title of host publicationGENSIPS'07 - 5th IEEE International Workshop on Genomic Signal Processing and Statistics
DOIs
Publication statusPublished - 2007
Event5th IEEE International Workshop on Genomic Signal Processing and Statistics, GENSIPS'07 - Tuusula, Finland
Duration: Jun 10 2007Jun 12 2007

Other

Other5th IEEE International Workshop on Genomic Signal Processing and Statistics, GENSIPS'07
CountryFinland
CityTuusula
Period6/10/076/12/07

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ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Computer Science Applications
  • Signal Processing
  • Electrical and Electronic Engineering

Cite this

Gowda, T., Leshner, S., Vrudhula, S., & Kim, S. (2007). Threshold logic gene regulatory networks. In GENSIPS'07 - 5th IEEE International Workshop on Genomic Signal Processing and Statistics [4365826] https://doi.org/10.1109/GENSIPS.2007.4365826