Three new alkaloids, convolutamines F and G, and convolutamydine E, from the Floridian marine bryozoan Amathia convoluta

Yoshiaki Kamano, Ayano Kotake, Hirofumi Hashima, Ichiro Hayakawa, Hatsue Hiraide, Hui Ping Zhang, Haruhisa Kizu, Kanki Komiyama, Masahiko Hayashi, George Pettit

Research output: Contribution to journalArticle

36 Scopus citations

Abstract

Two new (2-phenylethyl)amine alkaloids, convolutamines F and G, and a dibromohydroxy-oxindole alkaloid, convolutamydine E, have been isolated from the butan-1-ol soluble material of the Floridian marine bryozoan Amathia convoluta. Their structures were elucidated on the basis of spectroscopic data. Convolutamine F exhibited activity against KB, KB/VJ-300, and U937 cells. This compound also exhibited the inhibitory effects for cell division of fertilized sea urchin eggs.

Original languageEnglish (US)
Pages (from-to)1147-1153
Number of pages7
JournalCollection of Czechoslovak Chemical Communications
Volume64
Issue number7
DOIs
StatePublished - Jan 1 1999

Keywords

  • (2-phenylethyl)amine alkaloids
  • 3-hydroxyindol-2(3H)-one
  • Amathia convoluta
  • Bryozoa
  • Convolutamine F
  • Convolutamine G
  • Convolutamydine E
  • Cytostatic activity
  • Isolation
  • Marine natural products

ASJC Scopus subject areas

  • Chemistry(all)

Fingerprint Dive into the research topics of 'Three new alkaloids, convolutamines F and G, and convolutamydine E, from the Floridian marine bryozoan Amathia convoluta'. Together they form a unique fingerprint.

  • Cite this