Three-dimensional microfluidic flow field characterization with partical image velocimetry and laser scanning confocal microscopy

S. H. Chao, M. R. Holl, L. S. Jang, D. R. Meldrum

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Particle image velocimetry (PIV) provides a non-invasive, microfluidics compatible approach for characterization of flow fields in μTAS systems. This paper describes the application of confocal microscopy to improve the spatial resolution of PIV thereby enabling measurement of fine detail in flow fields by using the superior resolution and optical sectioning ability of confocal imaging. The three-dimensional velocity field present in a microchamber driven by a piezoelectric diaphragm was measured using this approach. Experimental results confirm the role of acoustic streaming in the generation of the velocity profiles.

Original languageEnglish (US)
Title of host publicationMicro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference
Subtitle of host publication9th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PublisherTransducer Research Foundation
Pages109-111
Number of pages3
ISBN (Print)0974361119, 9780974361116
StatePublished - Jan 1 2005
Externally publishedYes
Event9th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2005 - Boston, MA, United States
Duration: Oct 9 2005Oct 13 2005

Publication series

NameMicro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences
Volume1

Other

Other9th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2005
CountryUnited States
CityBoston, MA
Period10/9/0510/13/05

Keywords

  • Confocal microscopy
  • Flow field characterization
  • Microfluidics
  • Particle image velocimetry (PIV)

ASJC Scopus subject areas

  • Chemical Engineering (miscellaneous)
  • Bioengineering

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  • Cite this

    Chao, S. H., Holl, M. R., Jang, L. S., & Meldrum, D. R. (2005). Three-dimensional microfluidic flow field characterization with partical image velocimetry and laser scanning confocal microscopy. In Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 109-111). (Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences; Vol. 1). Transducer Research Foundation.