The role of the PGE 2-aromatase pathway in obesity-associated breast inflammation

Dingzhi Wang, Raymond N. DuBois

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Subbaramaiah and colleagues present the first evidence indicating that a cyclooxygenase-2- prostaglandin E 2-aromatase pathway promotes obesity-associated inflammation in women's breast tissues. Their findings shed new light on obesity-associated inflammation in general and provide a rationale for developing effective chemopreventive and therapeutic strategies targeting this pathway for obese women with breast inflammation and patients with hormone-dependent breast cancer.

Original languageEnglish (US)
Pages (from-to)308-310
Number of pages3
JournalCancer Discovery
Volume2
Issue number4
DOIs
StatePublished - Apr 2012
Externally publishedYes

Fingerprint

Aromatase
Prostaglandins E
Breast
Obesity
Inflammation
Cyclooxygenase 2
Hormones
Breast Neoplasms
Therapeutics

ASJC Scopus subject areas

  • Oncology

Cite this

The role of the PGE 2-aromatase pathway in obesity-associated breast inflammation. / Wang, Dingzhi; DuBois, Raymond N.

In: Cancer Discovery, Vol. 2, No. 4, 04.2012, p. 308-310.

Research output: Contribution to journalArticle

Wang, Dingzhi ; DuBois, Raymond N. / The role of the PGE 2-aromatase pathway in obesity-associated breast inflammation. In: Cancer Discovery. 2012 ; Vol. 2, No. 4. pp. 308-310.
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