The role of the PGE 2-aromatase pathway in obesity-associated breast inflammation

Dingzhi Wang, Raymond N. DuBois

    Research output: Contribution to journalArticlepeer-review

    5 Scopus citations


    Subbaramaiah and colleagues present the first evidence indicating that a cyclooxygenase-2- prostaglandin E 2-aromatase pathway promotes obesity-associated inflammation in women's breast tissues. Their findings shed new light on obesity-associated inflammation in general and provide a rationale for developing effective chemopreventive and therapeutic strategies targeting this pathway for obese women with breast inflammation and patients with hormone-dependent breast cancer.

    Original languageEnglish (US)
    Pages (from-to)308-310
    Number of pages3
    JournalCancer discovery
    Issue number4
    StatePublished - Apr 2012

    ASJC Scopus subject areas

    • Oncology


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