The Role of ABO-Incompatible Living Donors in Kidney Transplantation: State of the Art

James Thielke; Bruce Kaplan; Enrico Benedetti

doi:10.1016/j.semnephrol.2007.03.003

The Role of ABO-Incompatible Living Donors in Kidney Transplantation: State of the Art

James Thielke, Bruce Kaplan, Enrico Benedetti

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

Summary: In the past, ABO incompatibility has been considered an absolute contraindication for living donor kidney transplantation. Over the past 25 years, advances in immunosuppressive therapy and progressively more refined desensitization protocols have allowed increasingly successful transplantations across the ABO barrier. Current results of kidney transplants from ABO-incompatible living donors are quite favorable and comparable in the long term with the outcome of ABO-compatible organs both in Japan and in the United States. The present article reviews the history, outcomes, and current issues in kidney transplantation with ABO-incompatible living donors in adult and pediatric recipients.

Original language	English (US)
Pages (from-to)	408-413
Number of pages	6
Journal	Seminars in Nephrology
Volume	27
Issue number	4
DOIs	https://doi.org/10.1016/j.semnephrol.2007.03.003
State	Published - Jul 2007

Keywords

ABO incompatibility
hyperacute rejection
living donor kidney transplantation

ASJC Scopus subject areas

Nephrology

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10.1016/j.semnephrol.2007.03.003

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title = "The Role of ABO-Incompatible Living Donors in Kidney Transplantation: State of the Art",

abstract = "Summary: In the past, ABO incompatibility has been considered an absolute contraindication for living donor kidney transplantation. Over the past 25 years, advances in immunosuppressive therapy and progressively more refined desensitization protocols have allowed increasingly successful transplantations across the ABO barrier. Current results of kidney transplants from ABO-incompatible living donors are quite favorable and comparable in the long term with the outcome of ABO-compatible organs both in Japan and in the United States. The present article reviews the history, outcomes, and current issues in kidney transplantation with ABO-incompatible living donors in adult and pediatric recipients.",

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N2 - Summary: In the past, ABO incompatibility has been considered an absolute contraindication for living donor kidney transplantation. Over the past 25 years, advances in immunosuppressive therapy and progressively more refined desensitization protocols have allowed increasingly successful transplantations across the ABO barrier. Current results of kidney transplants from ABO-incompatible living donors are quite favorable and comparable in the long term with the outcome of ABO-compatible organs both in Japan and in the United States. The present article reviews the history, outcomes, and current issues in kidney transplantation with ABO-incompatible living donors in adult and pediatric recipients.

AB - Summary: In the past, ABO incompatibility has been considered an absolute contraindication for living donor kidney transplantation. Over the past 25 years, advances in immunosuppressive therapy and progressively more refined desensitization protocols have allowed increasingly successful transplantations across the ABO barrier. Current results of kidney transplants from ABO-incompatible living donors are quite favorable and comparable in the long term with the outcome of ABO-compatible organs both in Japan and in the United States. The present article reviews the history, outcomes, and current issues in kidney transplantation with ABO-incompatible living donors in adult and pediatric recipients.

KW - ABO incompatibility

KW - hyperacute rejection

KW - living donor kidney transplantation

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The Role of ABO-Incompatible Living Donors in Kidney Transplantation: State of the Art

Abstract

Keywords

ASJC Scopus subject areas

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