The Role of ABO-Incompatible Living Donors in Kidney Transplantation: State of the Art

James Thielke, Bruce Kaplan, Enrico Benedetti

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

Summary: In the past, ABO incompatibility has been considered an absolute contraindication for living donor kidney transplantation. Over the past 25 years, advances in immunosuppressive therapy and progressively more refined desensitization protocols have allowed increasingly successful transplantations across the ABO barrier. Current results of kidney transplants from ABO-incompatible living donors are quite favorable and comparable in the long term with the outcome of ABO-compatible organs both in Japan and in the United States. The present article reviews the history, outcomes, and current issues in kidney transplantation with ABO-incompatible living donors in adult and pediatric recipients.

Original languageEnglish (US)
Pages (from-to)408-413
Number of pages6
JournalSeminars in Nephrology
Volume27
Issue number4
DOIs
StatePublished - Jul 1 2007

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Keywords

  • ABO incompatibility
  • hyperacute rejection
  • living donor kidney transplantation

ASJC Scopus subject areas

  • Nephrology

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