The resurgence of acyclic nucleic acids

Su Zhang; Christopher Switzer; John C. Chaput

doi:10.1002/cbdv.200900281

The resurgence of acyclic nucleic acids

Su Zhang, Christopher Switzer, John C. Chaput

Molecular Sciences, School of (SMS)

Research output: Contribution to journal › Review article › peer-review

28 Scopus citations

Abstract

This review examines acyclic nucleoside analogs as therapeutic agents, potential progenitor candidates to RNA, and novel building blocks for nucleic-acid nanotechnology. Together, these areas of research provide new insights into the structural and functional properties of nucleic acids and suggest new paradigms for nucleic acid self-assembly.

Original language	English (US)
Pages (from-to)	245-258
Number of pages	14
Journal	Chemistry and Biodiversity
Volume	7
Issue number	2
DOIs	https://doi.org/10.1002/cbdv.200900281
State	Published - Feb 2010

ASJC Scopus subject areas

Bioengineering
Biochemistry
General Chemistry
Molecular Medicine
Molecular Biology

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10.1002/cbdv.200900281

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abstract = "This review examines acyclic nucleoside analogs as therapeutic agents, potential progenitor candidates to RNA, and novel building blocks for nucleic-acid nanotechnology. Together, these areas of research provide new insights into the structural and functional properties of nucleic acids and suggest new paradigms for nucleic acid self-assembly.",

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The resurgence of acyclic nucleic acids

Abstract

ASJC Scopus subject areas

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