TY - JOUR
T1 - The relevance of fractional amplitude of low-frequency fluctuation to interference effect
AU - Deng, Yuqin
AU - Wang, Yan
AU - Ding, Xiaoqian
AU - Tang, Yi Yuan
N1 - Funding Information:
We thank lab members for assistance with RS-fMRI data collection. This work was supported by the Office of Naval Research .
Publisher Copyright:
© 2015 Elsevier B.V..
PY - 2016/1/1
Y1 - 2016/1/1
N2 - Growing evidence has indicated a potential connection between resting-state functional magnetic resonance imaging (RS-fMRI) signal and cognitive performance. However, the relationship between intrinsic neural activity and behavioral interference effect on cognitive control has been poorly understood. In the present study, seventy-eight healthy subjects underwent RS-fMRI and performed Multi-Source Interference Task (MSIT). The fractional amplitude of low-frequency fluctuation (fALFF) was measured as an indicator of intrinsic brain activity. The difference in reaction times between interference and control conditions in MSIT was evaluated as interference effect. Then we examined the associations between fALFF and interference effect using partial correlation analysis controlling for age, gender and mean framewise displacement. The results demonstrated that fALFF values in orbital prefrontal cortex (OPFC) and right inferior frontal cortex (IFC) were negatively correlated with the interference effect in MSIT. The findings manifest that OPFC and right IFC may influence the processing efficiency of cognitive conflict and play a crucial role in cognitive control.
AB - Growing evidence has indicated a potential connection between resting-state functional magnetic resonance imaging (RS-fMRI) signal and cognitive performance. However, the relationship between intrinsic neural activity and behavioral interference effect on cognitive control has been poorly understood. In the present study, seventy-eight healthy subjects underwent RS-fMRI and performed Multi-Source Interference Task (MSIT). The fractional amplitude of low-frequency fluctuation (fALFF) was measured as an indicator of intrinsic brain activity. The difference in reaction times between interference and control conditions in MSIT was evaluated as interference effect. Then we examined the associations between fALFF and interference effect using partial correlation analysis controlling for age, gender and mean framewise displacement. The results demonstrated that fALFF values in orbital prefrontal cortex (OPFC) and right inferior frontal cortex (IFC) were negatively correlated with the interference effect in MSIT. The findings manifest that OPFC and right IFC may influence the processing efficiency of cognitive conflict and play a crucial role in cognitive control.
KW - Fractional amplitude of low-frequency fluctuation
KW - Interference effect
KW - Multi-source interference task
KW - Resting-state functional magnetic resonance imaging
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U2 - 10.1016/j.bbr.2015.08.014
DO - 10.1016/j.bbr.2015.08.014
M3 - Article
C2 - 26300450
AN - SCOPUS:84961181410
SN - 0166-4328
VL - 296
SP - 401
EP - 407
JO - Behavioural Brain Research
JF - Behavioural Brain Research
ER -