The natural history of primary biliary cirrhosis

Mohamad H. Imam, Keith Lindor

Research output: Contribution to journalArticle

24 Scopus citations

Abstract

Our understanding of the natural history of primary biliary cirrhosis (PBC) has been evolving especially following the introduction of ursodeoxycholic acid (UDCA). A clearer understanding of disease pathophysiology and earlier diagnosis with increased prevalence of the disease worldwide has led to increased interest and improved outcomes in patients with PBC. In this article, the authors touch briefly on features of the disease and describe the natural history of PBC prior to and after the introduction of UDCA.

Original languageEnglish (US)
Pages (from-to)329-333
Number of pages5
JournalSeminars in Liver Disease
Volume34
Issue number3
DOIs
StatePublished - Aug 2014

Keywords

  • liver transplantation
  • primary biliary cirrhosis
  • ursodeoxycholic acid

ASJC Scopus subject areas

  • Hepatology

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