The molecular basis of triazine-herbicide resistance in higher-plant chloroplasts

Joseph Hirschber, Anthony Bleecker, David J. Kyle, Lee McIntosh, Charles J. Arntzen

Research output: Contribution to journalArticlepeer-review

117 Scopus citations


Triazine herbicides inhibit photosynthesis by blocking electron transport in photosystem II. The target site ofthe herbicide was identified as a chloroplast thylakoid polypeptide (the QB protein) of 32,000 daltons. Studies of triazine-resistant weed biotypes suggested that a subtle change in the QB protein caused the resistance. We have cloned the chloroplast gene (psbA) that codes this protein from herbicide-resistant and herbicide-susceptible biotypes of Solanum nigrum. By DN A sequencing we detected a single base substitution in the psbA gene of the resistant plants, resulting in an amino acid change (serine to glycine for the susceptible to resistance conversion). This mutation is exactly the same one which we have described in a herbicide-resistant biotype of Amaranthus hybridus.

Original languageEnglish (US)
Pages (from-to)412-420
Number of pages9
JournalZeitschrift fur Naturforschung - Section C Journal of Biosciences
Issue number5
StatePublished - May 1 1984
Externally publishedYes


  • Chloroplasts
  • Molecular Basis of Herbicide-Resistance
  • Photosynthesis
  • Triazines

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)


Dive into the research topics of 'The molecular basis of triazine-herbicide resistance in higher-plant chloroplasts'. Together they form a unique fingerprint.

Cite this