The Lang strain of reovirus serotype 1 and the dearing strain of reovirus serotype 3 differ in their sensitivities to beta interferon

Bertram Jacobs, Rick E. Ferguson

Research output: Contribution to journalComment/debate

27 Scopus citations

Abstract

Replication of the Dearing strain of reovirus serotype 3 in mouse L cells was decreased 17- to 100-fold when a saturating dose of beta interferon (1,000 IU/ml) was used. Replication of the Lang strain of reovirus serotype 1 was inhibited only two- to threefold under similar conditions. It therefore appears that closely related strains of reovirus differ in their sensitivities to beta interferon treatment of mouse L cells.

Original languageEnglish (US)
Pages (from-to)5102-5104
Number of pages3
JournalJournal of virology
Volume65
Issue number9
StatePublished - Jan 1 1991

ASJC Scopus subject areas

  • Microbiology
  • Immunology
  • Insect Science
  • Virology

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