TY - JOUR
T1 - The influence of temperature alterations on eccentric contraction-induced isometric force and desmin loss in ratmedial gastrocnemius muscle
AU - Vasaghi-Gharamaleki, Behnoosh
AU - Keshavarz, Mansoor
AU - Gharibzadeh, Shahryar
AU - Sotodeh, Masoud
AU - Marvi, Hamidreza
AU - Mosayebnejad, Javad
AU - Takamjani, Ismail Ebrahimi
PY - 2008/2/15
Y1 - 2008/2/15
N2 - In this study isolated perfused rat muscle was used to examine the direct effect of temperature changes on the eccentric contraction-induced force and desmin loss. The left medial gastrocnemius muscle was separated and the entire lower limb was transferred into a prewarmed (35°C) organ bath. Temperature was adjusted to 31 or 39°C before and during eccentric contractions. Maximal isometric force and desmin loss were measured after 15 isometric or eccentric contractions. According to our data, organ bath temperature changes before or during eccentric contractions had no significant effect on force loss. However, a strong correlation between desmin loss and temperature changes before (r = 0.93, p<0.05) and during (r = 0.87, p<0.05) eccentric contractions was observed. Present results suggest that cooling before or during eccentric contractions may decrease desmin loss.
AB - In this study isolated perfused rat muscle was used to examine the direct effect of temperature changes on the eccentric contraction-induced force and desmin loss. The left medial gastrocnemius muscle was separated and the entire lower limb was transferred into a prewarmed (35°C) organ bath. Temperature was adjusted to 31 or 39°C before and during eccentric contractions. Maximal isometric force and desmin loss were measured after 15 isometric or eccentric contractions. According to our data, organ bath temperature changes before or during eccentric contractions had no significant effect on force loss. However, a strong correlation between desmin loss and temperature changes before (r = 0.93, p<0.05) and during (r = 0.87, p<0.05) eccentric contractions was observed. Present results suggest that cooling before or during eccentric contractions may decrease desmin loss.
KW - Desmin
KW - Eccentric contraction
KW - Isolated perfused muscle
KW - Isometric force loss
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U2 - 10.3923/jms.2008.162.169
DO - 10.3923/jms.2008.162.169
M3 - Article
AN - SCOPUS:51749097328
SN - 1682-4474
VL - 8
SP - 162
EP - 169
JO - Journal of Medical Sciences
JF - Journal of Medical Sciences
IS - 2
ER -