Abstract

Good quality crystalline sol-derived Hydroxyapatite (HA) thin films of thickness ∼350 nm on titanium substrates with underlying micro-channels were prepared by microwave annealing at a temperature of 400°C for 30 min. A comprehensive in-vitro study was conducted to assess the osteoblast adhesive response to the well-defined micro-scale topographical features on HA coated and uncoated surfaces. The study confirmed the osteoblast's response to the HA coated micro-channels with an elongated morphology. The effects to morphology suggest that osteoblast adhesion can be improved through optimal micro-channel design and may provide baseline design cues for improving the long-term performance of prosthetic orthopedic and dental implants.

Original languageEnglish (US)
Pages (from-to)569-572
Number of pages4
JournalKey Engineering Materials
Volume284-286
StatePublished - 2005

Fingerprint

Osteoblasts
Durapatite
Hydroxyapatite
Sol-gels
Substrates
Dental prostheses
Orthopedics
Polymethyl Methacrylate
Sols
Prosthetics
Titanium
Adhesives
Adhesion
Microwaves
Annealing
Crystalline materials
Thin films
Temperature

Keywords

  • Hydroxyapatite
  • Microwave annealing
  • Osteoblasts
  • Topographical features

ASJC Scopus subject areas

  • Ceramics and Composites
  • Chemical Engineering (miscellaneous)

Cite this

The influence of geometrically configured sol-gel derived hydroxyapatite substrates on osteoblast response. / Adams, Daniel; Smith, Regina D.; Malgas, Gerald F.; Massia, Stephen; Alford, Terry; Mayer, J. W.

In: Key Engineering Materials, Vol. 284-286, 2005, p. 569-572.

Research output: Contribution to journalArticle

Adams, Daniel ; Smith, Regina D. ; Malgas, Gerald F. ; Massia, Stephen ; Alford, Terry ; Mayer, J. W. / The influence of geometrically configured sol-gel derived hydroxyapatite substrates on osteoblast response. In: Key Engineering Materials. 2005 ; Vol. 284-286. pp. 569-572.
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