Abstract

Good quality crystalline sol-derived Hydroxyapatite (HA) thin films of thickness ∼350 nm on titanium substrates with underlying micro-channels were prepared by microwave annealing at a temperature of 400°C for 30 min. A comprehensive in-vitro study was conducted to assess the osteoblast adhesive response to the well-defined micro-scale topographical features on HA coated and uncoated surfaces. The study confirmed the osteoblast's response to the HA coated micro-channels with an elongated morphology. The effects to morphology suggest that osteoblast adhesion can be improved through optimal micro-channel design and may provide baseline design cues for improving the long-term performance of prosthetic orthopedic and dental implants.

Original languageEnglish (US)
Pages (from-to)569-572
Number of pages4
JournalKey Engineering Materials
Volume284-286
Publication statusPublished - 2005

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Keywords

  • Hydroxyapatite
  • Microwave annealing
  • Osteoblasts
  • Topographical features

ASJC Scopus subject areas

  • Ceramics and Composites
  • Chemical Engineering (miscellaneous)

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