The influence of geographic and climate factors on the timing of dengue epidemics in Perú, 1994-2008

Gerardo Chowell, Bernard Cazelles, Hélène Broutin, Cesar V. Munayco

Research output: Contribution to journalArticle

50 Citations (Scopus)

Abstract

Background: Dengue fever is a mosquito-borne disease that affects between 50 and 100 million people each year. Increasing our understanding of the heterogeneous transmission patterns of dengue at different spatial scales could have considerable public health value by guiding intervention strategies.Methods: Based on the weekly number of dengue cases in Perú by province, we investigated the association between dengue incidence during the period 1994-2008 and demographic and climate factors across geographic regions of the country.Results: Our findings support the presence of significant differences in the timing of dengue epidemics between jungle and coastal regions, with differences significantly associated with the timing of the seasonal cycle of mean temperature.Conclusions: Dengue is highly persistent in jungle areas of Perú where epidemics peak most frequently around March when rainfall is abundant. Differences in the timing of dengue epidemics in jungle and coastal regions are significantly associated with the seasonal temperature cycle. Our results suggest that dengue is frequently imported into coastal regions through infective sparks from endemic jungle areas and/or cities of other neighboring endemic countries, where propitious environmental conditions promote year-round mosquito breeding sites. If jungle endemic areas are responsible for multiple dengue introductions into coastal areas, our findings suggest that curtailing the transmission of dengue in these most persistent areas could lead to significant reductions in dengue incidence in coastal areas where dengue incidence typically reaches low levels during the dry season.

Original languageEnglish (US)
Article number164
JournalBMC Infectious Diseases
Volume11
DOIs
StatePublished - Jun 8 2011

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Geography
Dengue
Climate
Culicidae
Incidence
Temperature
Breeding
Public Health

Keywords

  • Climatic factors
  • Community size
  • Dengue
  • Dynamics
  • Epidemic timing
  • Perú
  • Wavelet analysis
  • Wavelet coherence

ASJC Scopus subject areas

  • Infectious Diseases

Cite this

The influence of geographic and climate factors on the timing of dengue epidemics in Perú, 1994-2008. / Chowell, Gerardo; Cazelles, Bernard; Broutin, Hélène; Munayco, Cesar V.

In: BMC Infectious Diseases, Vol. 11, 164, 08.06.2011.

Research output: Contribution to journalArticle

Chowell, Gerardo ; Cazelles, Bernard ; Broutin, Hélène ; Munayco, Cesar V. / The influence of geographic and climate factors on the timing of dengue epidemics in Perú, 1994-2008. In: BMC Infectious Diseases. 2011 ; Vol. 11.
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