The first human infection with severe fever with thrombocytopenia syndrome virus in Shaanxi Province, China

Jing Wei, Shen Li, Jian Hua Dong, Hui Tian, Gerardo Chowell, Huai Yu Tian, Wen Lv, Zong Qi Han, Bing Xu, Peng Bo Yu, Jing Jun Wang

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

Background: Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease discovered in China in 2009. In July 2013, the first human infection with SFTS virus (SFTSV) was detected in Shaanxi Province, Western China. Methods: A seroprevalence study among humans was carried out in an SFTS endemic village; specifically, serum samples were collected from 363 farmers in an SFTS endemic village in Shaanxi Province. The presence of SFTSV antibodies in serum was determined using an ELISA. Results: SFTSV antibodies were found in a total of 20 people (5.51%), with no significant difference between males and females (6.93% and 4.42%, respectively; Chi-square = 1.29, p= 0.25). Moreover, the SFTSV antibody positive rate was not significantly different across different age groups (Chi-square = 2.23, p= 0.69). Conclusions: SFTSV readily infects humans with outdoor exposure. The results of the serological study indicate that the virus circulates widely in Shaanxi Province. SFTSV represents a public health threat in China.

Original languageEnglish (US)
Pages (from-to)e37-e39
JournalInternational Journal of Infectious Diseases
Volume35
DOIs
StatePublished - Jun 1 2015

Keywords

  • Bunyaviridae
  • Epidemiological characteristic
  • Prevalence
  • Severe fever with thrombocytopenia syndrome

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

Fingerprint Dive into the research topics of 'The first human infection with severe fever with thrombocytopenia syndrome virus in Shaanxi Province, China'. Together they form a unique fingerprint.

  • Cite this

    Wei, J., Li, S., Dong, J. H., Tian, H., Chowell, G., Tian, H. Y., Lv, W., Han, Z. Q., Xu, B., Yu, P. B., & Wang, J. J. (2015). The first human infection with severe fever with thrombocytopenia syndrome virus in Shaanxi Province, China. International Journal of Infectious Diseases, 35, e37-e39. https://doi.org/10.1016/j.ijid.2015.02.014