The first human infection with severe fever with thrombocytopenia syndrome virus in Shaanxi Province, China

Jing Wei; Shen Li; Jian Hua Dong; Hui Tian; Gerardo Chowell; Huai Yu Tian; Wen Lv; Zong Qi Han; Bing Xu; Peng Bo Yu; Jing Jun Wang

doi:10.1016/j.ijid.2015.02.014

The first human infection with severe fever with thrombocytopenia syndrome virus in Shaanxi Province, China

Jing Wei, Shen Li, Jian Hua Dong, Hui Tian, Gerardo Chowell, Huai Yu Tian, Wen Lv, Zong Qi Han, Bing Xu, Peng Bo Yu, Jing Jun Wang

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

Background: Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease discovered in China in 2009. In July 2013, the first human infection with SFTS virus (SFTSV) was detected in Shaanxi Province, Western China. Methods: A seroprevalence study among humans was carried out in an SFTS endemic village; specifically, serum samples were collected from 363 farmers in an SFTS endemic village in Shaanxi Province. The presence of SFTSV antibodies in serum was determined using an ELISA. Results: SFTSV antibodies were found in a total of 20 people (5.51%), with no significant difference between males and females (6.93% and 4.42%, respectively; Chi-square = 1.29, p= 0.25). Moreover, the SFTSV antibody positive rate was not significantly different across different age groups (Chi-square = 2.23, p= 0.69). Conclusions: SFTSV readily infects humans with outdoor exposure. The results of the serological study indicate that the virus circulates widely in Shaanxi Province. SFTSV represents a public health threat in China.

Original language	English (US)
Pages (from-to)	e37-e39
Journal	International Journal of Infectious Diseases
Volume	35
DOIs	https://doi.org/10.1016/j.ijid.2015.02.014
State	Published - Jun 1 2015
Externally published	Yes

Keywords

Bunyaviridae
Epidemiological characteristic
Prevalence
Severe fever with thrombocytopenia syndrome

ASJC Scopus subject areas

Microbiology (medical)
Infectious Diseases

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10.1016/j.ijid.2015.02.014

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@article{28597a96d28343869da5c536c5809482,

title = "The first human infection with severe fever with thrombocytopenia syndrome virus in Shaanxi Province, China",

abstract = "Background: Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease discovered in China in 2009. In July 2013, the first human infection with SFTS virus (SFTSV) was detected in Shaanxi Province, Western China. Methods: A seroprevalence study among humans was carried out in an SFTS endemic village; specifically, serum samples were collected from 363 farmers in an SFTS endemic village in Shaanxi Province. The presence of SFTSV antibodies in serum was determined using an ELISA. Results: SFTSV antibodies were found in a total of 20 people (5.51%), with no significant difference between males and females (6.93% and 4.42%, respectively; Chi-square = 1.29, p= 0.25). Moreover, the SFTSV antibody positive rate was not significantly different across different age groups (Chi-square = 2.23, p= 0.69). Conclusions: SFTSV readily infects humans with outdoor exposure. The results of the serological study indicate that the virus circulates widely in Shaanxi Province. SFTSV represents a public health threat in China.",

keywords = "Bunyaviridae, Epidemiological characteristic, Prevalence, Severe fever with thrombocytopenia syndrome",

author = "Jing Wei and Shen Li and Dong, {Jian Hua} and Hui Tian and Gerardo Chowell and Tian, {Huai Yu} and Wen Lv and Han, {Zong Qi} and Bing Xu and Yu, {Peng Bo} and Wang, {Jing Jun}",

note = "Funding Information: This work was supported by the Chinese National Science and Technology Major Project (grant number 2013ZX10004202), the Shaanxi Provincial Department of Science and Technology (grant numbers 2013K12-04-02), and the National Research Program of the Ministry of Science and Technology, China (grant numbers 2012CB955501, 2012AA12A407, 2013AA122003). Publisher Copyright: {\textcopyright} 2015 Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.",

year = "2015",

month = jun,

day = "1",

doi = "10.1016/j.ijid.2015.02.014",

language = "English (US)",

volume = "35",

pages = "e37--e39",

journal = "International Journal of Infectious Diseases",

issn = "1201-9712",

publisher = "Elsevier",

}

TY - JOUR

T1 - The first human infection with severe fever with thrombocytopenia syndrome virus in Shaanxi Province, China

AU - Wei, Jing

AU - Li, Shen

AU - Dong, Jian Hua

AU - Tian, Hui

AU - Chowell, Gerardo

AU - Tian, Huai Yu

AU - Lv, Wen

AU - Han, Zong Qi

AU - Xu, Bing

AU - Yu, Peng Bo

AU - Wang, Jing Jun

N1 - Funding Information: This work was supported by the Chinese National Science and Technology Major Project (grant number 2013ZX10004202), the Shaanxi Provincial Department of Science and Technology (grant numbers 2013K12-04-02), and the National Research Program of the Ministry of Science and Technology, China (grant numbers 2012CB955501, 2012AA12A407, 2013AA122003). Publisher Copyright: © 2015 Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.

PY - 2015/6/1

Y1 - 2015/6/1

N2 - Background: Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease discovered in China in 2009. In July 2013, the first human infection with SFTS virus (SFTSV) was detected in Shaanxi Province, Western China. Methods: A seroprevalence study among humans was carried out in an SFTS endemic village; specifically, serum samples were collected from 363 farmers in an SFTS endemic village in Shaanxi Province. The presence of SFTSV antibodies in serum was determined using an ELISA. Results: SFTSV antibodies were found in a total of 20 people (5.51%), with no significant difference between males and females (6.93% and 4.42%, respectively; Chi-square = 1.29, p= 0.25). Moreover, the SFTSV antibody positive rate was not significantly different across different age groups (Chi-square = 2.23, p= 0.69). Conclusions: SFTSV readily infects humans with outdoor exposure. The results of the serological study indicate that the virus circulates widely in Shaanxi Province. SFTSV represents a public health threat in China.

AB - Background: Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease discovered in China in 2009. In July 2013, the first human infection with SFTS virus (SFTSV) was detected in Shaanxi Province, Western China. Methods: A seroprevalence study among humans was carried out in an SFTS endemic village; specifically, serum samples were collected from 363 farmers in an SFTS endemic village in Shaanxi Province. The presence of SFTSV antibodies in serum was determined using an ELISA. Results: SFTSV antibodies were found in a total of 20 people (5.51%), with no significant difference between males and females (6.93% and 4.42%, respectively; Chi-square = 1.29, p= 0.25). Moreover, the SFTSV antibody positive rate was not significantly different across different age groups (Chi-square = 2.23, p= 0.69). Conclusions: SFTSV readily infects humans with outdoor exposure. The results of the serological study indicate that the virus circulates widely in Shaanxi Province. SFTSV represents a public health threat in China.

KW - Bunyaviridae

KW - Epidemiological characteristic

KW - Prevalence

KW - Severe fever with thrombocytopenia syndrome

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SN - 1201-9712

VL - 35

SP - e37-e39

JO - International Journal of Infectious Diseases

JF - International Journal of Infectious Diseases

ER -

The first human infection with severe fever with thrombocytopenia syndrome virus in Shaanxi Province, China

Abstract

Keywords

ASJC Scopus subject areas

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