The feasibility and acceptability of a pilot randomized controlled trial testing pharmacy-based HPV vaccine completion

Alexis Koskan, Morgan E. Zittel, Chong Lee, Omar Sanchez, Linda Alvarez, Deborah L. Helitzer

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Objective: Immunizing pharmacists can administer vaccines; however, they are less likely to administer adolescent vaccines such as vaccines that protect against human papillomavirus (HPV). Although past research has recommended incorporating pharmacists to increase adolescent vaccination, few intervention studies have tested healthcare delivery models that incorporate pharmacists to aid in vaccine series completion. This research explored the feasibility and acceptability of an intervention in which pharmacists administered booster doses of the HPV vaccine series. Methods: Between April 2019 and February 2020, the research team recruited participants for a pilot randomized controlled trial hosted in one federally qualified health center (FQHC) clinic. Researchers asked intervention group participants to complete the HPV vaccine series with their community pharmacists and control group participants to complete the series at their FQHC. We conducted a pre- and post-intervention surveys and in-depth interviews with both intervention and control group participants. Results: A total of 33 parents of children who received the first dose of the HPV vaccine enrolled in the study of whom 8 intervention and 11 control group participants completed post-intervention data collection. Although there were no statistically significant changes in vaccine completion and in psychometric variables, we did find that pharmacist-delivered HPV vaccination was acceptable, due, primarily, to convenience. Barriers to receiving pharmacist-administered vaccines included pharmacies’ lack of stocking the vaccine and insurance-related barriers to care. Conclusion: Although a promising and acceptable healthcare delivery approach, there are still barriers for caregivers to have their children vaccinated against HPV at their community pharmacies.

Original languageEnglish (US)
Pages (from-to)3038-3045
Number of pages8
JournalResearch in Social and Administrative Pharmacy
Issue number6
StatePublished - Jun 2022


  • HPV vaccine
  • Human papillomavirus (HPV)
  • Intervention
  • Pharmacist
  • Pharmacy

ASJC Scopus subject areas

  • Pharmacy
  • Pharmaceutical Science


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