67 Scopus citations

Abstract

Calls for the "translation" of research from bench to bedside are increasingly demanding. What is translation, and why does it matter? We sketch the recent history of outcome-oriented translational research in the United States, with a particular focus on the Roadmap Initiative of the National Institutes of Health (Bethesda, MD). Our main example of contemporary translational research is stem cell research, which has superseded genomics as the translational object of choice. We explore the nature of and obstacles to translational research and assess the ethical and biomedical challenges of embracing a translational ethos.

Original languageEnglish (US)
Pages (from-to)43-51
Number of pages9
JournalAmerican Journal of Bioethics
Volume8
Issue number3
DOIs
StatePublished - Mar 1 2008

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Keywords

  • History
  • National Institutes of Health
  • Stem cell research
  • Translational science

ASJC Scopus subject areas

  • Issues, ethics and legal aspects
  • Health Policy

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