The epidemiology of methicillin-resistant Staphylococcus aureus colonisation and infection

Research output: Contribution to journalArticle

46 Citations (Scopus)

Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) is an increasingly common nosocomial pathogen in health care facilities throughout the world. Overall, approximately two-thirds of nosocomial cases and outbreaks have occurred in critical care units. Major risk factors for colonisation and infection in nursing homes include age, underlying conditions, nasal colonisation and the presence of indwelling devices such as catheters, tracheostomies and nasogastric tubes. In general, patients with MRSA infections in an acute care facility are more likely to have had a prolonged hospital stay, to have received prior antibiotics and to have severe underlying disease, than patients infected with methicillin-susceptible S. aureus. Risk factors for MRSA bacteraemia include: a higher frequency of severe underlying disease, poorer underlying prognosis, prior antibiotic therapy, prolonged hospitalisation, intravascular catheterisation, and intensive care unit location. Risk factors for developing MRSA postoperative wound infections include: prior antimicrobial therapy, prolonged hospitalisation and severity of underlying disease. Little data are available to identify specific risk factors for colonisation or infection of burn wounds by MRSA.

Original languageEnglish (US)
Pages (from-to)99-103
Number of pages5
JournalJournal of Chemotherapy
Volume7
Issue numberSUPPL. 3
StatePublished - 1995
Externally publishedYes

Fingerprint

Methicillin-Resistant Staphylococcus aureus
Epidemiology
Infection
Hospitalization
Anti-Bacterial Agents
Surgical Wound Infection
Methicillin
Tracheostomy
Health Facilities
Wound Infection
Critical Care
Bacteremia
Nursing Homes
Nose
Catheterization
Disease Outbreaks
Intensive Care Units
Staphylococcus aureus
Length of Stay
Catheters

Keywords

  • Colonisation
  • Cross-infection
  • Epidemiology
  • Infection
  • Methicillin-resistance
  • Nosocomial
  • Risk factors
  • Staphylococcus aureus

ASJC Scopus subject areas

  • Microbiology (medical)
  • Pharmacology (medical)

Cite this

The epidemiology of methicillin-resistant Staphylococcus aureus colonisation and infection. / Doebbeling, Bradley.

In: Journal of Chemotherapy, Vol. 7, No. SUPPL. 3, 1995, p. 99-103.

Research output: Contribution to journalArticle

@article{b0782f083f454ddb8118e237bd7322d6,
title = "The epidemiology of methicillin-resistant Staphylococcus aureus colonisation and infection",
abstract = "Methicillin-resistant Staphylococcus aureus (MRSA) is an increasingly common nosocomial pathogen in health care facilities throughout the world. Overall, approximately two-thirds of nosocomial cases and outbreaks have occurred in critical care units. Major risk factors for colonisation and infection in nursing homes include age, underlying conditions, nasal colonisation and the presence of indwelling devices such as catheters, tracheostomies and nasogastric tubes. In general, patients with MRSA infections in an acute care facility are more likely to have had a prolonged hospital stay, to have received prior antibiotics and to have severe underlying disease, than patients infected with methicillin-susceptible S. aureus. Risk factors for MRSA bacteraemia include: a higher frequency of severe underlying disease, poorer underlying prognosis, prior antibiotic therapy, prolonged hospitalisation, intravascular catheterisation, and intensive care unit location. Risk factors for developing MRSA postoperative wound infections include: prior antimicrobial therapy, prolonged hospitalisation and severity of underlying disease. Little data are available to identify specific risk factors for colonisation or infection of burn wounds by MRSA.",
keywords = "Colonisation, Cross-infection, Epidemiology, Infection, Methicillin-resistance, Nosocomial, Risk factors, Staphylococcus aureus",
author = "Bradley Doebbeling",
year = "1995",
language = "English (US)",
volume = "7",
pages = "99--103",
journal = "Journal of Chemotherapy",
issn = "1120-009X",
publisher = "Maney Publishing",
number = "SUPPL. 3",

}

TY - JOUR

T1 - The epidemiology of methicillin-resistant Staphylococcus aureus colonisation and infection

AU - Doebbeling, Bradley

PY - 1995

Y1 - 1995

N2 - Methicillin-resistant Staphylococcus aureus (MRSA) is an increasingly common nosocomial pathogen in health care facilities throughout the world. Overall, approximately two-thirds of nosocomial cases and outbreaks have occurred in critical care units. Major risk factors for colonisation and infection in nursing homes include age, underlying conditions, nasal colonisation and the presence of indwelling devices such as catheters, tracheostomies and nasogastric tubes. In general, patients with MRSA infections in an acute care facility are more likely to have had a prolonged hospital stay, to have received prior antibiotics and to have severe underlying disease, than patients infected with methicillin-susceptible S. aureus. Risk factors for MRSA bacteraemia include: a higher frequency of severe underlying disease, poorer underlying prognosis, prior antibiotic therapy, prolonged hospitalisation, intravascular catheterisation, and intensive care unit location. Risk factors for developing MRSA postoperative wound infections include: prior antimicrobial therapy, prolonged hospitalisation and severity of underlying disease. Little data are available to identify specific risk factors for colonisation or infection of burn wounds by MRSA.

AB - Methicillin-resistant Staphylococcus aureus (MRSA) is an increasingly common nosocomial pathogen in health care facilities throughout the world. Overall, approximately two-thirds of nosocomial cases and outbreaks have occurred in critical care units. Major risk factors for colonisation and infection in nursing homes include age, underlying conditions, nasal colonisation and the presence of indwelling devices such as catheters, tracheostomies and nasogastric tubes. In general, patients with MRSA infections in an acute care facility are more likely to have had a prolonged hospital stay, to have received prior antibiotics and to have severe underlying disease, than patients infected with methicillin-susceptible S. aureus. Risk factors for MRSA bacteraemia include: a higher frequency of severe underlying disease, poorer underlying prognosis, prior antibiotic therapy, prolonged hospitalisation, intravascular catheterisation, and intensive care unit location. Risk factors for developing MRSA postoperative wound infections include: prior antimicrobial therapy, prolonged hospitalisation and severity of underlying disease. Little data are available to identify specific risk factors for colonisation or infection of burn wounds by MRSA.

KW - Colonisation

KW - Cross-infection

KW - Epidemiology

KW - Infection

KW - Methicillin-resistance

KW - Nosocomial

KW - Risk factors

KW - Staphylococcus aureus

UR - http://www.scopus.com/inward/record.url?scp=0028838567&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028838567&partnerID=8YFLogxK

M3 - Article

C2 - 8609545

AN - SCOPUS:0028838567

VL - 7

SP - 99

EP - 103

JO - Journal of Chemotherapy

JF - Journal of Chemotherapy

SN - 1120-009X

IS - SUPPL. 3

ER -