The effect of spontaneous mutations on competitive ability

S. Schaack, D. E. Allen, L. C. Latta, K. K. Morgan, M. Lynch

Research output: Contribution to journalArticle

11 Scopus citations

Abstract

Understanding the impact of spontaneous mutations on fitness has many theoretical and practical applications in biology. Although mutational effects on individual morphological or life-history characters have been measured in several classic genetic model systems, there are few estimates of the rate of decline due to mutation for complex fitness traits. Here, we estimate the effects of mutation on competitive ability, an important complex fitness trait, in a model system for ecological and evolutionary genomics, Daphnia. Competition assays were performed to compare fitness between mutation-accumulation (MA) lines and control lines from eight different genotypes from two populations of Daphnia pulicaria after 30 and 65 generations of mutation accumulation. Our results show a fitness decline among MA lines relative to controls as expected, but highlight the influence of genomic background on this effect. In addition, in some assays, MA lines outperform controls providing insight into the frequency of beneficial mutations.

Original languageEnglish (US)
Pages (from-to)451-456
Number of pages6
JournalJournal of Evolutionary Biology
Volume26
Issue number2
DOIs
StatePublished - Feb 2013
Externally publishedYes

Keywords

  • Competition
  • Daphnia
  • Fitness
  • Mutation

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics

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