The dolastatins 25. Conformational isomerism of N-benzyloxy-carbonyl-N-methylisoleucinol and related substances

George Pettit, Michael D. Williams, Jayaram K. Srirangam, Fiona Hogan, N. Leo Benoiton, Darko Kantoci

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

Conformational isomerism in a selection of N-Z-N-methylisoleucine derivatives was detected and investigated using variable temperature NMR spectroscopy. Thermodynamic values for the restricted rotation of conformational isomers were derived.

Original languageEnglish (US)
Pages (from-to)919-921
Number of pages3
JournalJournal of the Chemical Society, Perkin Transactions 2
DOIs
StatePublished - Jan 1 1995

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ASJC Scopus subject areas

  • Chemistry(all)

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