The diversity of experimental organisms in biomedical research may be influenced by biomedical funding

B. R. Erick Peirson, Heather Kropp, Julia Damerow, Manfred Laubichler

Research output: Contribution to journalReview article

8 Scopus citations

Abstract

Contrary to concerns of some critics, we present evidence that biomedical research is not dominated by a small handful of model organisms. An exhaustive analysis of research literature suggests that the diversity of experimental organisms in biomedical research has increased substantially since 1975. There has been a longstanding worry that organism-centric funding policies can lead to biases in experimental organism choice, and thus negatively impact the direction of research and the interpretation of results. Critics have argued that a focus on model organisms has unduly constrained the diversity of experimental organisms. The availability of large electronic databases of scientific literature, combined with interest in quantitative methods among philosophers of science, presents new opportunities for data-driven investigations into organism choice in biomedical research. The diversity of organisms used in NIH-funded research may be considerably lower than in the broader biomedical sciences, and may be subject to greater constraints on organism choice.

Original languageEnglish (US)
Article number1600258
JournalBioEssays
Volume39
Issue number5
DOIs
StatePublished - May 2017

Keywords

  • history of biology
  • model organisms
  • science policy
  • taxonomic diversity

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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