The advantage of live-donor kidney transplantation in older recipients

Lisa Nanovic, Bruce Kaplan

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Although renal transplantation confers a survival advantage over maintenance dialysis in patients with end-stage renal disease, many factors can attenuate this survival advantage over the long term. Among the most important negative influences on outcomes are older donor age, extended time on the transplant waiting list, and use of organs from deceased donors. Whether it is better to avoid prolonged waiting times for a standard criteria donor kidney by transplanting an organ from an older living donor is a clinically important question. In their analysis, Gill and colleagues have addressed this question for older transplant recipients. The investigators' primary finding is that survival after transplantation from an older living donor is at least equivalent to that after transplantation from a younger deceased donor (i.e. a standard criteria donor) and superior to that observed following transplantation from expanded criteria donors. Reasons that prevent a straightforward clinical application of such findings are discussed in this commentary.

Original languageEnglish (US)
Pages (from-to)18-19
Number of pages2
JournalNature Clinical Practice Nephrology
Volume5
Issue number1
DOIs
StatePublished - Jan 2009
Externally publishedYes

Fingerprint

Kidney Transplantation
Tissue Donors
Transplantation
Living Donors
Survival
Waiting Lists
Chronic Kidney Failure
Dialysis
Maintenance
Research Personnel
Transplants
Kidney

Keywords

  • Expanded criteria donor
  • Kidney transplantation
  • Living donor
  • Organ allocation
  • Standard criteria donor

ASJC Scopus subject areas

  • Nephrology

Cite this

The advantage of live-donor kidney transplantation in older recipients. / Nanovic, Lisa; Kaplan, Bruce.

In: Nature Clinical Practice Nephrology, Vol. 5, No. 1, 01.2009, p. 18-19.

Research output: Contribution to journalArticle

Nanovic, Lisa ; Kaplan, Bruce. / The advantage of live-donor kidney transplantation in older recipients. In: Nature Clinical Practice Nephrology. 2009 ; Vol. 5, No. 1. pp. 18-19.
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