Testosterone and opioids interact to regulate feeding in a male migratory songbird

Research output: Contribution to journalArticle

39 Scopus citations

Abstract

A male migratory songbird (dark-eyed junco, Junco hyemalis) was used as a model for studies on the influence of testosterone (T) on feeding, and on interactive effects on this behavior between T and the opioid antagonist naloxone hydrochloride (Nal). Administered chronically to birds exposed to nonstimulating photoperiods, T increased food intake by 30-58% without altering the body mass, the fat index, or the standard metabolic rate. An intramuscular injection of Nal decreased feeding temporarily in a dose-related manner. T-treated juncos exhibited a decreased sensitivity to the anorexic influence of Nal administration, demonstrating that T interacts with opioids to control food consumption. Neuroendocrine mechanisms that potentially account for this interaction are discussed.

Original languageEnglish (US)
Pages (from-to)394-405
Number of pages12
JournalHormones and Behavior
Volume26
Issue number3
DOIs
StatePublished - Sep 1992
Externally publishedYes

ASJC Scopus subject areas

  • Endocrinology
  • Endocrine and Autonomic Systems
  • Behavioral Neuroscience

Fingerprint Dive into the research topics of 'Testosterone and opioids interact to regulate feeding in a male migratory songbird'. Together they form a unique fingerprint.

  • Cite this