Synthesis of Tobacco Mosaic Virus Protein Sequence 81-851

George Pettit; William R. Jones

doi:10.1021/jo00806a002

Synthesis of Tobacco Mosaic Virus Protein Sequence 81-851

George Pettit, William R. Jones

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

The 81-85 segment of tobacco mosaic virus protein has been prepared by two different synthetic approaches. Synthesis of the protected pentapeptide N-benzyloxycarbonyl-L-threonyl-L-alanyl-L-leucyl-L-leucyl-glycine hydrazide corresponding to TMV protein 81-85 was accomplished employing as key step coupling of N-Z-Thr-Ala azide with Leu-Leu-Gly-OMe. The product was identical with the same pentapeptide obtained by a Merrifield solid-phase synthesis.

Original language	English (US)
Pages (from-to)	870-873
Number of pages	4
Journal	Journal of Organic Chemistry
Volume	36
Issue number	7
DOIs	https://doi.org/10.1021/jo00806a002
State	Published - Apr 1 1971

ASJC Scopus subject areas

Organic Chemistry

Access to Document

10.1021/jo00806a002

Cite this

@article{8ea1b4b5dd864fec808597514541d179,

title = "Synthesis of Tobacco Mosaic Virus Protein Sequence 81-851",

abstract = "The 81-85 segment of tobacco mosaic virus protein has been prepared by two different synthetic approaches. Synthesis of the protected pentapeptide N-benzyloxycarbonyl-L-threonyl-L-alanyl-L-leucyl-L-leucyl-glycine hydrazide corresponding to TMV protein 81-85 was accomplished employing as key step coupling of N-Z-Thr-Ala azide with Leu-Leu-Gly-OMe. The product was identical with the same pentapeptide obtained by a Merrifield solid-phase synthesis.",

author = "George Pettit and Jones, {William R.}",

year = "1971",

month = apr,

day = "1",

doi = "10.1021/jo00806a002",

language = "English (US)",

volume = "36",

pages = "870--873",

journal = "Journal of Organic Chemistry",

issn = "0022-3263",

publisher = "American Chemical Society",

number = "7",

}

TY - JOUR

T1 - Synthesis of Tobacco Mosaic Virus Protein Sequence 81-851

AU - Pettit, George

AU - Jones, William R.

PY - 1971/4/1

Y1 - 1971/4/1

N2 - The 81-85 segment of tobacco mosaic virus protein has been prepared by two different synthetic approaches. Synthesis of the protected pentapeptide N-benzyloxycarbonyl-L-threonyl-L-alanyl-L-leucyl-L-leucyl-glycine hydrazide corresponding to TMV protein 81-85 was accomplished employing as key step coupling of N-Z-Thr-Ala azide with Leu-Leu-Gly-OMe. The product was identical with the same pentapeptide obtained by a Merrifield solid-phase synthesis.

AB - The 81-85 segment of tobacco mosaic virus protein has been prepared by two different synthetic approaches. Synthesis of the protected pentapeptide N-benzyloxycarbonyl-L-threonyl-L-alanyl-L-leucyl-L-leucyl-glycine hydrazide corresponding to TMV protein 81-85 was accomplished employing as key step coupling of N-Z-Thr-Ala azide with Leu-Leu-Gly-OMe. The product was identical with the same pentapeptide obtained by a Merrifield solid-phase synthesis.

UR - http://www.scopus.com/inward/record.url?scp=0015216188&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0015216188&partnerID=8YFLogxK

U2 - 10.1021/jo00806a002

DO - 10.1021/jo00806a002

M3 - Article

C2 - 5550266

AN - SCOPUS:0015216188

SN - 0022-3263

VL - 36

SP - 870

EP - 873

JO - Journal of Organic Chemistry

JF - Journal of Organic Chemistry

IS - 7

ER -

Synthesis of Tobacco Mosaic Virus Protein Sequence 81-851

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this