Synthesis of tobacco mosaic virus protein sequence 81-85

George Pettit, William R. Jones

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

The 81-85 segment of tobacco mosaic virus protein has been prepared by two different synthetic approaches. Synthesis of the protected pentapeptide N-benzyloxycarbonyl-L-threonyl-L-alanyl-L-leucyl-L-leucyl-glycine hydrazide corresponding to TMV protein 81-85 was accomplished employing as key step coupling of N-Z-Thr-Ala azide with Leu-Leu-Gly-OMe. The product was identical with the same pentapeptide obtained by a Merrifield solid-phase synthesis.

Original languageEnglish (US)
Pages (from-to)870-873
Number of pages4
JournalJournal of Organic Chemistry
Volume36
Issue number7
StatePublished - 1971

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Tobacco
Viruses
Azides
Proteins
glycine hydrazide

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

Synthesis of tobacco mosaic virus protein sequence 81-85. / Pettit, George; Jones, William R.

In: Journal of Organic Chemistry, Vol. 36, No. 7, 1971, p. 870-873.

Research output: Contribution to journalArticle

Pettit, George ; Jones, William R. / Synthesis of tobacco mosaic virus protein sequence 81-85. In: Journal of Organic Chemistry. 1971 ; Vol. 36, No. 7. pp. 870-873.
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