Synthesis of the Carbohydrate Moiety of Bleomycin

Vince Pozsgay, Tadaaki Ohgi, Sidney M. Hecht

Research output: Contribution to journalArticle

12 Scopus citations

Abstract

The synthesis of the disaccharide 2-O-(3-O-carbamoyl-α-D-mannopyranosyl)-L-gulopyranose has been achieved in good yield via the silver triflate promoted coupling of 2,4,6-tri-O-acetyl-3-O-(N-acetylcarbamoyl)-α-D-mannopyranosyl bromide (7) with both benzyl 3,4,6-tri-O-benzyl-β-L-gulopyranoside (5) and 3,4-di-O-benzyl-1,6-anhydro-β-L-gulopyranose (12).

Original languageEnglish (US)
Pages (from-to)3761-3763
Number of pages3
JournalJournal of Organic Chemistry
Volume46
Issue number18
DOIs
StatePublished - Aug 1981
Externally publishedYes

ASJC Scopus subject areas

  • Organic Chemistry

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