SYNTHESIS IN PROCESS DEVELOPMENT: ISSUES AND SOLUTION METHODOLOGIES.

George Stephanopoulos, D. William Townsend

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Abstract

Synthesis issues at the process development stage generate large combinatorial problems whose solution has a profound effect on the feasibility and optimality of the resulting processing schemes. This paper deals with the formulation of various such synthesis problems, examines their principal characteristics and how these scope the solution procedures. In particular, the paper addresses the following issues and methodologies: How topological characteristics of the search space define patterns which can be exploited for the systematic generation of attractive chemical production schemes. What characteristics define targeting procedures and evolutionary syntheses for the design of molecules with desired physical properties. How a knowledge-based expert system is designed for the synthesis of feasible and attractive biochemical pathways.

Original languageEnglish (US)
Title of host publicationInstitution of Chemical Engineers Symposium Series
PublisherInst of Chemical Engineers, Rugby, Engl. Distributed by Pergamon Press
Pages427-441
Number of pages15
Edition92
ISBN (Print)0852951884
StatePublished - Dec 1 1985
Externally publishedYes

Publication series

NameInstitution of Chemical Engineers Symposium Series
Number92
ISSN (Print)0307-0492

ASJC Scopus subject areas

  • Chemical Engineering(all)

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    Stephanopoulos, G., & Townsend, D. W. (1985). SYNTHESIS IN PROCESS DEVELOPMENT: ISSUES AND SOLUTION METHODOLOGIES. In Institution of Chemical Engineers Symposium Series (92 ed., pp. 427-441). (Institution of Chemical Engineers Symposium Series; No. 92). Inst of Chemical Engineers, Rugby, Engl. Distributed by Pergamon Press.