TY - GEN
T1 - SYNTHESIS IN PROCESS DEVELOPMENT
T2 - ISSUES AND SOLUTION METHODOLOGIES.
AU - Stephanopoulos, George
AU - Townsend, D. William
PY - 1985/12/1
Y1 - 1985/12/1
N2 - Synthesis issues at the process development stage generate large combinatorial problems whose solution has a profound effect on the feasibility and optimality of the resulting processing schemes. This paper deals with the formulation of various such synthesis problems, examines their principal characteristics and how these scope the solution procedures. In particular, the paper addresses the following issues and methodologies: How topological characteristics of the search space define patterns which can be exploited for the systematic generation of attractive chemical production schemes. What characteristics define targeting procedures and evolutionary syntheses for the design of molecules with desired physical properties. How a knowledge-based expert system is designed for the synthesis of feasible and attractive biochemical pathways.
AB - Synthesis issues at the process development stage generate large combinatorial problems whose solution has a profound effect on the feasibility and optimality of the resulting processing schemes. This paper deals with the formulation of various such synthesis problems, examines their principal characteristics and how these scope the solution procedures. In particular, the paper addresses the following issues and methodologies: How topological characteristics of the search space define patterns which can be exploited for the systematic generation of attractive chemical production schemes. What characteristics define targeting procedures and evolutionary syntheses for the design of molecules with desired physical properties. How a knowledge-based expert system is designed for the synthesis of feasible and attractive biochemical pathways.
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M3 - Conference contribution
AN - SCOPUS:0022286355
SN - 0852951884
T3 - Institution of Chemical Engineers Symposium Series
SP - 427
EP - 441
BT - Institution of Chemical Engineers Symposium Series
PB - Inst of Chemical Engineers, Rugby, Engl. Distributed by Pergamon Press
ER -