Successful orthotopic liver transplantation in a patient with refractory biliary candidiasis

Keith B. Noack, Doug R. Osmon, Ken P. Batts, Mark Wilhelm, Ruud A F Krom, Keith Lindor

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

The authors present a nonimmunocompromised patient who developed refractory fungal (Candida albicans) cholangitis and who subsequently underwent successful orthotopic liver transplantation for progressive destruction of intrahepatic and extrahepatic bile ducts. Liver biopsy specimens showed periductal abscesses, and cholangiograms showed rapidly progressive destruction of intrahepatic and extrahepatic bile ducts. Standard immunosuppressive therapy and perioperative amphotericin B were administered. At 6 months, the patient was clinically well with no evidence of recurrent biliary candidiasis. The authors suggest that orthotopic liver transplantation may be a reasonable therapeutic option for patients with refractory biliary candidiasis.

Original languageEnglish (US)
Pages (from-to)1728-1730
Number of pages3
JournalGastroenterology
Volume101
Issue number6
StatePublished - 1991
Externally publishedYes

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Candidiasis
Liver Transplantation
Intrahepatic Bile Ducts
Extrahepatic Bile Ducts
Cholangitis
Amphotericin B
Immunosuppressive Agents
Candida albicans
Abscess
Biopsy
Liver
Therapeutics

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Noack, K. B., Osmon, D. R., Batts, K. P., Wilhelm, M., Krom, R. A. F., & Lindor, K. (1991). Successful orthotopic liver transplantation in a patient with refractory biliary candidiasis. Gastroenterology, 101(6), 1728-1730.

Successful orthotopic liver transplantation in a patient with refractory biliary candidiasis. / Noack, Keith B.; Osmon, Doug R.; Batts, Ken P.; Wilhelm, Mark; Krom, Ruud A F; Lindor, Keith.

In: Gastroenterology, Vol. 101, No. 6, 1991, p. 1728-1730.

Research output: Contribution to journalArticle

Noack, KB, Osmon, DR, Batts, KP, Wilhelm, M, Krom, RAF & Lindor, K 1991, 'Successful orthotopic liver transplantation in a patient with refractory biliary candidiasis', Gastroenterology, vol. 101, no. 6, pp. 1728-1730.
Noack, Keith B. ; Osmon, Doug R. ; Batts, Ken P. ; Wilhelm, Mark ; Krom, Ruud A F ; Lindor, Keith. / Successful orthotopic liver transplantation in a patient with refractory biliary candidiasis. In: Gastroenterology. 1991 ; Vol. 101, No. 6. pp. 1728-1730.
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