Substantial production of drosophilin A methyl ether (tetrachloro-1,4-dimethoxybenzene) by the lignicolous basidiomycete Phellinus badius in the heartwood of mesquite (Prosopis juliflora) trees

Laurence Garvie, Barry Wilkens, Thomas L. Groy, Jessie A. Glaeser

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Toxic organohalogen pollutants produced as by-products of industrial processes, such as chloroform and polychlorinated dibenzo-p-dioxins, also have significant natural sources. A substantial terrestrial source of halogenated organics originates from fungal decay of wood and leaf litter. Here we show that the lignicolous basidiomycete Phellinus badius deposits up to 30,000 mg of the halogenated metabolite drosophilin A methyl ether (DAME, tetrachloro-1,4-dimethoxybenzene) per kilogram of decayed heartwood in the mesquite Prosopis juliflora. DAME occurs as clusters of glassy crystals up to 1 mm long within the decayed heartwood. In addition, the Phellinus badius basidiocarps contain an average of 24,000 mg DAME/kg dried fruiting body, testifying to the significant translocation and accumulation of Cl accompanied by DAME biosynthesis. The high DAME concentrations attest to the substantial Cl content of the heartwood, which averages near 5,000 ppm, with Cl/K near 1:1, consistent with an inorganic chloride precursor. Phellinus badius has a circumglobal distribution in the tropics and subtropics, where it is widely distributed on hardwoods and commonly associated with decay of mesquite. There is the potential for extensive DAME formation within decayed heartwood worldwide given the extensive range of Phellinus badius and its propensity to form DAME within mesquites. Further, DAME production is not limited to Phellinus badius but occurs in a range of lignicolous basidiomycetes, suggesting a significant natural reservoir for this chloroaromatic with potential environmental implications.

Original languageEnglish (US)
Pages (from-to)1-8
Number of pages8
JournalScience of Nature
Volume102
Issue number3-4
DOIs
StatePublished - Apr 1 2015

Fingerprint

Phellinus
Prosopis juliflora
Prosopis
heartwood
Basidiomycota
ether
ethers
organohalogen
fruiting
chloroform
leaf litter
dioxin
translocation
metabolite
chloride
crystal
pollutant
polychlorinated dibenzodioxins
basidiomata
decayed wood

Keywords

  • Chlorinated hydroquinone metabolites
  • DAME
  • Drosophilins
  • Organohalogen pollutants
  • Phellinus badius
  • Prosopis juliflora

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics

Cite this

Substantial production of drosophilin A methyl ether (tetrachloro-1,4-dimethoxybenzene) by the lignicolous basidiomycete Phellinus badius in the heartwood of mesquite (Prosopis juliflora) trees. / Garvie, Laurence; Wilkens, Barry; Groy, Thomas L.; Glaeser, Jessie A.

In: Science of Nature, Vol. 102, No. 3-4, 01.04.2015, p. 1-8.

Research output: Contribution to journalArticle

@article{e81bd64f42cf4f12b12566655e98a71a,
title = "Substantial production of drosophilin A methyl ether (tetrachloro-1,4-dimethoxybenzene) by the lignicolous basidiomycete Phellinus badius in the heartwood of mesquite (Prosopis juliflora) trees",
abstract = "Toxic organohalogen pollutants produced as by-products of industrial processes, such as chloroform and polychlorinated dibenzo-p-dioxins, also have significant natural sources. A substantial terrestrial source of halogenated organics originates from fungal decay of wood and leaf litter. Here we show that the lignicolous basidiomycete Phellinus badius deposits up to 30,000 mg of the halogenated metabolite drosophilin A methyl ether (DAME, tetrachloro-1,4-dimethoxybenzene) per kilogram of decayed heartwood in the mesquite Prosopis juliflora. DAME occurs as clusters of glassy crystals up to 1 mm long within the decayed heartwood. In addition, the Phellinus badius basidiocarps contain an average of 24,000 mg DAME/kg dried fruiting body, testifying to the significant translocation and accumulation of Cl accompanied by DAME biosynthesis. The high DAME concentrations attest to the substantial Cl content of the heartwood, which averages near 5,000 ppm, with Cl/K near 1:1, consistent with an inorganic chloride precursor. Phellinus badius has a circumglobal distribution in the tropics and subtropics, where it is widely distributed on hardwoods and commonly associated with decay of mesquite. There is the potential for extensive DAME formation within decayed heartwood worldwide given the extensive range of Phellinus badius and its propensity to form DAME within mesquites. Further, DAME production is not limited to Phellinus badius but occurs in a range of lignicolous basidiomycetes, suggesting a significant natural reservoir for this chloroaromatic with potential environmental implications.",
keywords = "Chlorinated hydroquinone metabolites, DAME, Drosophilins, Organohalogen pollutants, Phellinus badius, Prosopis juliflora",
author = "Laurence Garvie and Barry Wilkens and Groy, {Thomas L.} and Glaeser, {Jessie A.}",
year = "2015",
month = "4",
day = "1",
doi = "10.1007/s00114-015-1268-5",
language = "English (US)",
volume = "102",
pages = "1--8",
journal = "Naturwissenschaften",
issn = "0028-1042",
publisher = "Springer Verlag",
number = "3-4",

}

TY - JOUR

T1 - Substantial production of drosophilin A methyl ether (tetrachloro-1,4-dimethoxybenzene) by the lignicolous basidiomycete Phellinus badius in the heartwood of mesquite (Prosopis juliflora) trees

AU - Garvie, Laurence

AU - Wilkens, Barry

AU - Groy, Thomas L.

AU - Glaeser, Jessie A.

PY - 2015/4/1

Y1 - 2015/4/1

N2 - Toxic organohalogen pollutants produced as by-products of industrial processes, such as chloroform and polychlorinated dibenzo-p-dioxins, also have significant natural sources. A substantial terrestrial source of halogenated organics originates from fungal decay of wood and leaf litter. Here we show that the lignicolous basidiomycete Phellinus badius deposits up to 30,000 mg of the halogenated metabolite drosophilin A methyl ether (DAME, tetrachloro-1,4-dimethoxybenzene) per kilogram of decayed heartwood in the mesquite Prosopis juliflora. DAME occurs as clusters of glassy crystals up to 1 mm long within the decayed heartwood. In addition, the Phellinus badius basidiocarps contain an average of 24,000 mg DAME/kg dried fruiting body, testifying to the significant translocation and accumulation of Cl accompanied by DAME biosynthesis. The high DAME concentrations attest to the substantial Cl content of the heartwood, which averages near 5,000 ppm, with Cl/K near 1:1, consistent with an inorganic chloride precursor. Phellinus badius has a circumglobal distribution in the tropics and subtropics, where it is widely distributed on hardwoods and commonly associated with decay of mesquite. There is the potential for extensive DAME formation within decayed heartwood worldwide given the extensive range of Phellinus badius and its propensity to form DAME within mesquites. Further, DAME production is not limited to Phellinus badius but occurs in a range of lignicolous basidiomycetes, suggesting a significant natural reservoir for this chloroaromatic with potential environmental implications.

AB - Toxic organohalogen pollutants produced as by-products of industrial processes, such as chloroform and polychlorinated dibenzo-p-dioxins, also have significant natural sources. A substantial terrestrial source of halogenated organics originates from fungal decay of wood and leaf litter. Here we show that the lignicolous basidiomycete Phellinus badius deposits up to 30,000 mg of the halogenated metabolite drosophilin A methyl ether (DAME, tetrachloro-1,4-dimethoxybenzene) per kilogram of decayed heartwood in the mesquite Prosopis juliflora. DAME occurs as clusters of glassy crystals up to 1 mm long within the decayed heartwood. In addition, the Phellinus badius basidiocarps contain an average of 24,000 mg DAME/kg dried fruiting body, testifying to the significant translocation and accumulation of Cl accompanied by DAME biosynthesis. The high DAME concentrations attest to the substantial Cl content of the heartwood, which averages near 5,000 ppm, with Cl/K near 1:1, consistent with an inorganic chloride precursor. Phellinus badius has a circumglobal distribution in the tropics and subtropics, where it is widely distributed on hardwoods and commonly associated with decay of mesquite. There is the potential for extensive DAME formation within decayed heartwood worldwide given the extensive range of Phellinus badius and its propensity to form DAME within mesquites. Further, DAME production is not limited to Phellinus badius but occurs in a range of lignicolous basidiomycetes, suggesting a significant natural reservoir for this chloroaromatic with potential environmental implications.

KW - Chlorinated hydroquinone metabolites

KW - DAME

KW - Drosophilins

KW - Organohalogen pollutants

KW - Phellinus badius

KW - Prosopis juliflora

UR - http://www.scopus.com/inward/record.url?scp=84926211487&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84926211487&partnerID=8YFLogxK

U2 - 10.1007/s00114-015-1268-5

DO - 10.1007/s00114-015-1268-5

M3 - Article

VL - 102

SP - 1

EP - 8

JO - Naturwissenschaften

JF - Naturwissenschaften

SN - 0028-1042

IS - 3-4

ER -