Stylopeptide 2, a proline-rich cyclodecapeptide from the sponge Stylotella sp.

Mary R. Brennan; Catherine E. Costello; Simin D. Maleknia; George Pettit; Karen L. Erickson

doi:10.1021/np0704856

Stylopeptide 2, a proline-rich cyclodecapeptide from the sponge Stylotella sp.

Mary R. Brennan, Catherine E. Costello, Simin D. Maleknia, George Pettit, Karen L. Erickson

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Abstract

A new proline-rich cyclodecapeptide, designated stylopeptide 2, has been isolated from a cytotoxic extract of the Papua New Guinea marine sponge Stylotella sp. and found to correspond to structure 1. The structural assignment was based on HRMS collision-induced dissociation tandem mass spectrometry (CID MS/MS), NMR spectroscopic data, and amino acid analysis, which led to assignment of the absolute configuration.

Original language	English (US)
Pages (from-to)	453-456
Number of pages	4
Journal	Journal of Natural Products
Volume	71
Issue number	3
DOIs	https://doi.org/10.1021/np0704856
State	Published - Mar 2008

ASJC Scopus subject areas

Analytical Chemistry
Molecular Medicine
Pharmacology
Pharmaceutical Science
Drug Discovery
Complementary and alternative medicine
Organic Chemistry

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10.1021/np0704856

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abstract = "A new proline-rich cyclodecapeptide, designated stylopeptide 2, has been isolated from a cytotoxic extract of the Papua New Guinea marine sponge Stylotella sp. and found to correspond to structure 1. The structural assignment was based on HRMS collision-induced dissociation tandem mass spectrometry (CID MS/MS), NMR spectroscopic data, and amino acid analysis, which led to assignment of the absolute configuration.",

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AU - Erickson, Karen L.

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AB - A new proline-rich cyclodecapeptide, designated stylopeptide 2, has been isolated from a cytotoxic extract of the Papua New Guinea marine sponge Stylotella sp. and found to correspond to structure 1. The structural assignment was based on HRMS collision-induced dissociation tandem mass spectrometry (CID MS/MS), NMR spectroscopic data, and amino acid analysis, which led to assignment of the absolute configuration.

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Stylopeptide 2, a proline-rich cyclodecapeptide from the sponge Stylotella sp.

Abstract

ASJC Scopus subject areas

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