Study of the effects of ionic liquids on lipid bilayers

Taylor T. Young, Stephen A. Sarles, Tianyu Wu, Matthew Green, Timothy E. Long, Donald J. Leo

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The formation of lipid bilayers between ionic liquid droplets is presented as a new means of forming functional bimolecular networks. Ionic liquids are molten salts that have a number of interesting properties, such as the ability to be a liquid at room temperature and exceedingly low vapor pressure. Our research demonstrates that it is possible to consistently and repeatable form lipid bilayers on droplets of ionic liquid solutions. Characterization of the bilayers interfaces shows that the ionic liquids have negligible effects on the stability and electrical properties of the bilayer. It is also shown that the conductance levels in the gating events of Alamethicin peptide are affected by some ionic liquids.

Original languageEnglish (US)
Title of host publicationBioinspiration, Biomimetics, and Bioreplication 2012
DOIs
StatePublished - May 14 2012
Externally publishedYes
EventBioinspiration, Biomimetics, and Bioreplication 2012 - San Diego, CA, United States
Duration: Mar 12 2012Mar 15 2012

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume8339
ISSN (Print)0277-786X

Other

OtherBioinspiration, Biomimetics, and Bioreplication 2012
CountryUnited States
CitySan Diego, CA
Period3/12/123/15/12

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Keywords

  • Alamethicin
  • Droplet interface lipid bilayer
  • Ionic liquid
  • Regulated attachment method

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

Cite this

Young, T. T., Sarles, S. A., Wu, T., Green, M., Long, T. E., & Leo, D. J. (2012). Study of the effects of ionic liquids on lipid bilayers. In Bioinspiration, Biomimetics, and Bioreplication 2012 [833906] (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 8339). https://doi.org/10.1117/12.915078